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TranscriptomicsNINJA connects JAZ proteins to the co-repressor TOPLESS
NINJA (At4g28910) and TOPLESS proteins function as negative regulators of jasmonate responses. Our results point to TPL proteins as general co-repressors that affect multiple signalling pathways through the interaction with specific adaptor proteins. This new insight reveals how stress- and growth-...
ORGANISM(S): Arabidopsis thaliana 
2010-04-05 | E-GEOD-19455 | biostudies-arrayexpress
TranscriptomicsGM00156 EMETINE TIME COURSE
GM00156 (Coriell) cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treated an...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1490 | biostudies-arrayexpress
TranscriptomicsLNCaP EMETINE TIME COURSE
LNCaP prostate cancer cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treate...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1488 | biostudies-arrayexpress
TranscriptomicsPC3 EMETINE TIME COURSE
PC3 prostate cancer cells were treated with and without 100?g/ml Emetine Dihydrochloride Hydrate (Fluka, Buchs, Swizerland). Both Emetine-treated and untreated control cells were then incubated at 37°C for 10 hours. After the incubation, the first time point (0 min) was harvested for both treated ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1489 | biostudies-arrayexpress
TranscriptomicsRetionic acid gene expression time series in human embryonic stem cells
Retinoic acid RA time course experiment: H1 cells(WiCell Research Institute, WA01, Passage40) maintained in TeSR1 were treated with 1uM retinoic acid (RA) in a detailed time course:day0,day0.5,day1,day1.5,day2,day3, day4 and day5 . Total RNA was prepared by usage of the Qiagen RNA extraction kit. m...
ORGANISM(S): Homo sapiens 
2007-09-13 | E-GEOD-8439 | biostudies-arrayexpress
TranscriptomicsThe RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
Deletion of the flap loop in the Rp2 subunit of human RNAPII did not alter the ability of human RNAPII to initiate transcription or elongate the initiated transcripts in vivo and in vitro, and was also dispensable for elongation factor-mediated enhancement and inhibition of transcript elongation in ...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-29734 | biostudies-arrayexpress
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