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TranscriptomicsGene expression data in the retina in HIV positive and HIV negative eyes
To examine the gene expression data in the retina in HIV positive and HIV negative autopsy eyes we used a microarray approach with the HumanHT-12 v4 Expression BeadChip.



Retinal punches were made for the following regions



CWS = cotton wool spot

IRH = intra-retina...
ORGANISM(S): Homo sapiens 
2013-09-20 | E-MEXP-3757 | biostudies-arrayexpress
GenomicsOpen Chromatin by DNaseI HS from ENCODE/OpenChrom(Duke University)
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Terry Furey mailto:tsfurey@duke.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). These tracks displa...
ORGANISM(S): Homo sapiens 
2011-10-14 | E-GEOD-32970 | biostudies-arrayexpress
ProteomicsLC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian Decoction on the postoperative intestinal adhesion of rats
This study aims to explore the therapeutic effects of KN decoction in a PIA rat model, as well as its potential mechanisms via metabolomics and proteomics analyses.
ORGANISM(S): Rattus Norvegicus 
2024-09-09 | PXD055723 |
ProteomicsK562 Chemical arrest cell cycle phase fractions 2D-MS-CETSA
K562 cells were synchronized by double thymidine block(DTB) based chemical arrest scheme into G1/S, S and Prometaphase(PM) fractions. Three biological replicates were collected on different days, and assembled into a 2D-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC,54ºC ...
ORGANISM(S): Homo Sapiens (human) 
2018-05-08 | PXD009146 | JPOST Repository
ProteomicsK562 Elutriation cell cycle phase fractions 2D-MS-CETSA
K562 cells were synchronized by cell size difference based Elutriation scheme into G1, S and G2 fractions. Three biological replicates were collected on different days, and assembled into a 2D-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC,54ºC and 57ºC), (Figure 1A, Meth...
ORGANISM(S): Homo Sapiens (human) 
2018-05-08 | PXD009171 | JPOST Repository
TranscriptomicsA dynamic H3K27ac signature defines VEGF-regulated endothelial enhancers
Histone modifications are now well-established regulators of transcriptional programs that distinguish distinct cell states. However, the kinetics of histone modification and their role in mediating rapid, signal-responsive changes in gene expression have been little studied on a genome-wide scale. ...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-41166 | biostudies-arrayexpress
ProteomicsIMPRINTS-CETSA, 5-FU in parental and 5-FU-resistant HCT15 cells
Parental and 5-fluorouracil (5-FU)-resistant HCT15 cells were treated with 5-FU or vehicle for 12h and assembled into an IMPRINTS-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC, 54ºC, and 57ºC) with each set of samples heated at one temperature included in the same isobar...
ORGANISM(S): Homo Sapiens (human) 
2021-07-15 | PXD026472 | JPOST Repository
ProteomicsIMPRINTS-CETSA, FUDR and FUR in MCF7 cells, 2h and 12h incubation
MCF7 cells were treated with floxuridine (FUDR), fluorouridine (FUR), or vehicle and assembled into an IMPRINTS-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC, 54ºC, and 57ºC) with each set of samples heated at one temperature included in the same isobaric TMT10 set and m...
ORGANISM(S): Homo Sapiens (human) 
2021-07-15 | PXD026471 | JPOST Repository
TranscriptomicsDirect GR binding sites potentiate clusters of TF binding across the human genome [7]
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-79430 | biostudies-arrayexpress
GenomicsDNaseI/FAIRE/ChIP Synthesis from ENCODE/OpenChrom(Duke/UNC/UTA)
These tracks display a synthesis of evidence from different assays as part of the four Open Chromatin track sets. This track displays open chromatin regions and/or transcription factor binding sites identified in multiple cell types by one or more complementary methodologies, DNaseI hypersensitivity...
ORGANISM(S): Homo sapiens 
2012-09-12 | E-GEOD-40833 | biostudies-arrayexpress
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