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MetabolomicsTo investigate the effects of long-term continuous soil drought on the rhizosphere metabolic environment
To examine whether drought-conditioned microbiome restructuring coincided with changes in rhizosphere metabolites, we profiled rhizosphere metabolomes across the three conditioning generations.
2026-07-02 | MTBLS14920 | MetaboLights
TranscriptomicsIdentification and functional characterization of long noncoding RNAs in breast cancer
In this study, we have integrated RNA-seq data from subcellular fractionated RNA (i.e., cytoplasm, nucleoplasm, and chromatin-associated) with GRO-seq data using a novel bioinformatics pipeline. This has yielded a comprehensive catalog of polyadenylated lncRNAs in MCF-7 cells, about half of which ha...
ORGANISM(S): Homo sapiens 
2015-07-30 | E-GEOD-63189 | biostudies-arrayexpress
TranscriptomicsLong noncoding RNA as modular scaffold of histone modification complexes
This SuperSeries is composed of the following subset Series: GSE22343: ChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-H3K4me2, anti-LSD1 or anti-SUZ12 antibodies on HOX tiling array GSE22344: ChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-LSD1 or anti...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22345 | biostudies-arrayexpress
TranscriptomicsChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-LSD1 or anti-SUZ12 antibodies on human HG18 Nimblegen promoter arrays
Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic inheritance. Here we show that the lincRNA HOTAIR serves as a scaffold for at least two distinct histone modification complexes. A 5’ domain of HOTAIR binds Polycomb Repressive Complex 2 (PRC2) while a 3’ domain of H...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-22344 | biostudies-arrayexpress
TranscriptomicsChIP-chip of siGFP- or siHOTAIR-treated foreskin fibroblasts with anti-H3K4me2, anti-LSD1 or anti-SUZ12 antibodies on HOX tiling array
Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic inheritance. Here we show that the lincRNA HOTAIR serves as a scaffold for at least two distinct histone modification complexes. A 5’ domain of HOTAIR binds Polycomb Repressive Complex 2 (PRC2) while a 3’ domain of H...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22343 | biostudies-arrayexpress
UnknownHippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis.
Not available
S-EPMC4772271 | biostudies-literature
MetabolomicsCharacterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling
This study centered on detecting potentially anti-inflammatory active constituents in ethanolic extracts of Chinese Lonicera species by taking an UHPLC-HRMS-based metabolite profiling approach. Extracts from eight different Lonicera species were subjected to both UHPLC-HRMS analysis and to pharmacol...
2022-11-17 | MTBLS3112 | MetaboLights
TranscriptomicsRNA-seq analysis of Tetrahymena thermophila
We present a comprehensive transcriptome of ciliate T. thermophila using the Illumina RNA-seq platform. The data was generated from the six mRNA samples of growth, starvation and conjugation of Tetrahymena. Despite an AT rich genome, there are about 124.6 million reads mapped to T. thermophila genom...
ORGANISM(S): Tetrahymena thermophila 
2012-03-15 | E-GEOD-27971 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profile of CYC2 K.O. and WT during meiosis in Tetrahymena thermophila
Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks (DSBs) made by the Spo11 protein. The present study shed light on the functional role of Cyclin, CYC2, in Tetrahymena thermophila which has transcriptionally high expression le...
ORGANISM(S): Tetrahymena thermophila 
2016-04-06 | E-GEOD-79286 | biostudies-arrayexpress
UnknownPrognostic role of long noncoding RNA ZFAS1 in cancer patients: a systematic review and meta-analysis.
Not available
S-EPMC5725037 | biostudies-literature
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