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MetabolomicsUntargeted metabolomics reveals alterations in metabolites of lipid metabolism and immune pathways in serum of rats after long term oral administration of Amalaki rasayana
Amalaki rasayana (AR), a traditional preparation is widely used by Ayurvedic physicians for the treatment of inflammatory conditions, cardiovascular diseases, cancer and for rejuvenating aged people. Metabolic alterations induced by Amalaki rasayana intervention are unknown. We aimed to investigate ...
2019-05-24 | MTBLS867 | MetaboLights
TranscriptomicsDNA Methylation Mediated by a MicroRNA Pathway
In plants, the known microRNAs (miRNAs) are produced as ~21 nucleotide (nt) duplexes from their precursors by Dicer like 1 (DCL1). They are incorporated into Argonaute 1 (AGO1) protein to regulate target gene expression primarily through mRNA cleavage. We report here the discovery of a new class of ...
ORGANISM(S): Oryza sativa 
2010-03-12 | E-GEOD-20748 | biostudies-arrayexpress
UnknownA Systematic Review and Meta-Analysis on a Disease in TCM: Astragalus Injection for Gathering Qi Depression.
Not available
S-EPMC7038034 | biostudies-literature
ProteomicsMulti-omics profiling reveals systemic rejuvenation of the aged kidney through senolytic therapy
Cellular senescence is a key driver of kidney aging, leading to functional decline and increased susceptibility to chronic kidney disease. While the senolytic combination of dasatinib and quercetin (D+Q) has shown promise in mitigating age-related pathologies, its long-term effects and underlying mu...
ORGANISM(S): Homo Sapiens 
2026-03-24 | PXD076057 |
UnknownThe Therapeutic Principle of Combined Strengthening Qi and Eliminating Pathogens in Treating Middle-Advanced Primary Liver Cancer: A Systematic Review and Meta-Analysis.
Not available
S-EPMC8578139 | biostudies-literature
GenomicsRNA polymerase V targets transcriptional silencing components to promoters of protein-coding genes
Transcriptional gene silencing controls transposons and other repetitive elements through RNA-directed DNA methylation (RdDM) and heterochromatin formation. A key component of the Arabidopsis RdDM pathway is ARGONAUTE4 (AGO4), which associates with sizs to mediate DNA methylation. Here, we show that...
ORGANISM(S): Arabidopsis thaliana 
2012-10-17 | E-GEOD-35381 | biostudies-arrayexpress
UnknownGlimpse of natural selection of long-lived T-cell clones in healthy life.
Not available
S-EPMC5024599 | biostudies-literature
ProteomicsComparative proteomic analysis of kidney distal convoluted tubule and cortical collecting duct cells following long-term hormonal stimulation
The distal convoluted tubule (DCT) and the cortical collecting ducts (CCD) are portions of renal tubule that are partly responsible for maintaining the systemic concentrations of potassium, sodium, calcium and magnesium. Despite being structurally similar, DCT and CCD cells have different transport ...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-15 | PXD005454 | Pride
Distal convoluted tubule Mouse Hormone Kidney Cortical collecting duct Long-term 
UnknownDiscovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometric methods.
Not available
S-EPMC9627220 | biostudies-literature
MetabolomicsMulti-omics reveals that alkaline mineral water improves the respiratory health and growth performance of transported calves

BACKGROUND: Long-distance transportation, a frequent practice in the cattle industry, stresses calves and results in morbidity, mortality and growth suppression, leading to welfare concerns and economic losses. Alkaline mineral water (AMW) is an electrolyte additive containing mu...

2024-06-04 | MTBLS8204 | MetaboLights
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