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UnknownL-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction.
Not available
S-EPMC4196986 | biostudies-literature
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39908 | biostudies-arrayexpress
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt
This SuperSeries is composed of the following subset Series: GSE39908: Bromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq] GSE39909: Bromodomain-dependent stage-specific male genome programming by Brdt [Illumina BeadArray] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39910 | biostudies-arrayexpress
TranscriptomicsBromodomain-dependent stage-specific male genome programming by Brdt [Illumina BeadArray]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39909 | biostudies-arrayexpress
TranscriptomicsEffect of ARF on the transcription of p53 target genes in homologous recombination deficient cells
ARF is a tumour suppressor activated by oncogenic stress, which stabilizes p53. Although p53 is a key component of the response to DNA damage, a similar function for ARF has not been ascribed. In this work we show that homologous recombination (HR) -deficient primary mouse and human cells accumulate...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-51354 | biostudies-arrayexpress
TranscriptomicsDNA-microarray of human breast cancer cell line MCF10A harboring PSD4 knock-out and wild-type control
To address the mechanism of action of EFA6B we have knocked-out its gene PSD4 using the CRISPR/Cas9 technology. The MCF10A human mammary cell line was used for the knock-out as it is a well-characterized normal human mammary cell line and thus enabled us to study the effect of deleting PSD4 in a non...
ORGANISM(S): Homo sapiens 
2021-03-01 | E-MTAB-10063 | biostudies-arrayexpress
UnknownColchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.
Not available
S-EPMC8159193 | biostudies-literature
GenomicsChromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B [ChIP-Seq]
The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental to the life cycle yet the underlying molecular details remain obscure. Here we show that an essential step is the genome-wide incorporation of TH2B, a histone H2B variant of hitherto unknown function. Using mous...
ORGANISM(S): Mus musculus 
2013-10-18 | E-GEOD-45915 | biostudies-arrayexpress
UnknownPrognostic Factors of Late-onset Hearing Loss in Infants With Congenital Cytomegalovirus and Normal Audiologic Assessment at Birth.
Not available
S-EPMC12688458 | biostudies-literature
UnknownIntegrating artificial intelligence into lung cancer screening: a randomised controlled trial protocol.
Not available
S-EPMC10868245 | biostudies-literature
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