Sort   by:  
 Page size 
UnknownPredictors of failure with high-flow nasal oxygen therapy in COVID-19 patients with acute respiratory failure: a multicenter observational study.

Purpose

We aimed to describe the use of high-flow nasal oxygen (HFNO) in patients with COVID-19 acute respiratory failure and factors associated with a shift to invasive mechanical ventilation.

Methods

This is a multicenter, observational study from a prospectively collected database ...
S-EPMC7934982 | biostudies-literature
UnknownAwake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study.

Background

Awake prone positioning (awake-PP) in non-intubated coronavirus disease 2019 (COVID-19) patients could avoid endotracheal intubation, reduce the use of critical care resources, and improve survival. We aimed to examine whether the combination of high-flow nasal oxygen therapy (HFN...
S-EPMC7537953 | biostudies-literature
UnknownHigh-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure.

Purpose

Whether the use of high-flow nasal oxygen in adult patients with COVID-19 associated acute respiratory failure improves clinically relevant outcomes remains unclear. We thus sought to assess the effect of high-flow nasal oxygen on ventilator-free days, compared to early initiation of...
S-EPMC7876530 | biostudies-literature
UnknownClinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS.

Purpose

The main characteristics of mechanically ventilated ARDS patients affected with COVID-19, and the adherence to lung-protective ventilation strategies are not well known. We describe characteristics and outcomes of confirmed ARDS in COVID-19 patients managed with invasive mechanical v...
S-EPMC7387884 | biostudies-literature
UnknownIdentification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study.

Background

The clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine whether clinical phenotypes of patients with COVID-19 can be derived from clinical data, to assess the reproducibility of these phenotypes and correlation with prognosis,...
S-EPMC7906623 | biostudies-literature
UnknownGenotyping, sequencing and analysis of 140,000 adults from Mexico City.
The Mexico City Prospective Study is a prospective cohort of more than 150,000 adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in Mexico City1. Here we generated genotype and exome-sequencing data for all individuals and whole-genome sequencing data fo...
S-EPMC10600010 | biostudies-literature
UnknownCharacteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain.

Objectives

To analyse the characteristics and predictors of death in hospitalized patients with coronavirus disease 2019 (COVID-19) in Spain.

Methods

A retrospective observational study was performed of the first consecutive patients hospitalized with COVID-19 confirmed by real-time P...
S-EPMC7399713 | biostudies-literature
UnknownLong-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial.

Background

For women with oestrogen receptor (ER)-positive early breast cancer, treatment with tamoxifen for 5 years substantially reduces the breast cancer mortality rate throughout the first 15 years after diagnosis. We aimed to assess the further effects of continuing tamoxifen to 10 year...
S-EPMC3596060 | biostudies-literature
UnknownFactors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.

Background

ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) did not find an overall reduction in cardiovascular events with an initial invasive versus conservative management strategy in chronic coronary disease; however, there were cons...
S-EPMC11187765 | biostudies-literature
UnknownEvaluation of appendicitis risk prediction models in adults with suspected appendicitis.

Background

Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa ...
S-EPMC6972511 | biostudies-literature
Sort   by:  
 Page size