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TranscriptomicsContribution of Veillonella parvula to Pseudomonas aeruginosa mediated pathogenicity in a murine tumor model system
We investigated the specific interactions of the most dominant bacterial CF-pathogen, Pseudomonas aeruginosa, and the anaerobic bacterium Veilllonella parvula, that has been recovered at comparable cell numbers in the respiratory tract of CF patients. We used our recently established in-vivo murine ...
ORGANISM(S): Veillonella parvula DSM 2008 
2014-11-06 | E-GEOD-58388 | biostudies-arrayexpress
ProteomicsRecruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B
HDX-MS of R15B and it's interactions with trimeric eIF2 substrate. Here we integrated diverse approaches to elucidate how the PP1 non-catalytic subu-nit PPP1R15B (R15B) captures its full trimeric eIF2 substrate. We found that the substrate recruitment module of R15B is largely disordered with three...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD047538 | Pride
Hdx-ms Hd-ms 
ProteomicsTemperature and Raw Material Impact on Gluten Digestibility and Immunoreactive Peptides in Wheat, Rye, and Barley
Peptides released from gluten proteins during gastrointestinal digestion can trigger various wheat-related disorders, including celiac disease (CeD), wheat allergy, and wheat allergy dependent on augmentation factors (WALDA). Our study aimed to identify and quantify these immunoreactive peptides (IP...
ORGANISM(S): Triticum aestivum (Wheat) Hordeum vulgare (Barley) Secale cereale 
2026-08-13 | PXD080314 | Pride
Mass spectrometry Wheat allergy Wheat-related disorders Celiac disease Infogest Proteomics Walda 
ProteomicsEnabling phenotypic drug discovery for neurological mitochondrial DNA disorders with patient-derived neural progenitor cells
Mitochondrial DNA (mtDNA) mutations predominantly cause neurological diseases. Searching for therapeutic strategies is hindered by the absence of viable neural model systems due to the challenges of engineering mtDNA. We demonstrate that neural progenitor cells (NPCs), rapidly obtained from human in...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080849 | MassIVE
ProteomicsAbsolute quantification of gluten protein groups and their relation to wheat baking quality
Wheat gluten proteins are key determinants of baking quality. While untargeted proteomics enable relative quantification, absolute quantities of specific gluten protein groups are not available so far. We developed a targeted liquid chromatography with tandem mass spectrometry (LC-MS/MS) stable isot...
ORGANISM(S): Triticum Aestivum 
2026-03-05 | PXD072549 | panorama
ProteomicsHigh throughput generation of a resource of the human secretome in mammalian cells
The proteins secreted by human tissues (the secretome) are important for the basic understanding of human biology, but also for identification of potential targets for future diagnosis and therapy. Here, we present an annotation of all predicted secreted proteins (n=2,623) with information about the...
ORGANISM(S): Homo Sapiens 
2021-03-15 | PXD012054 | panorama
UnknownA multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.
Not available
S-EPMC8742248 | biostudies-literature
UnknownThe Psychological Science Accelerator's COVID-19 rapid-response dataset.
Not available
S-EPMC9918828 | biostudies-literature
UnknownSame data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology.
Not available
S-EPMC11804095 | biostudies-literature
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