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UnknownThe core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.
Not available
S-EPMC7520014 | biostudies-literature
MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
MetabolomicsInsights into Metabolic Changes Caused by the Trichoderma virens-Maize Root Interaction
The interactions of crops with root-colonizing endophytic microorganisms are highly relevant to agriculture, because endophytes can modify plant resistance to pests and increase crop yields. We investigated the interactions between the host plant Zea mays and the endophytic fungus Trichode...
2021-07-08 | MTBLS1964 | MetaboLights
TranscriptomicsExpression analysis of murine bone marrow (BMDM) derived macrophages stimulated with C1q
Investigation of whole genome gene expression level changes in BMDM adhered for 4 or 18hrs to Lab Tek Chamber slides pre-coated with 4ug/ml of human serum albumin (HSA) (control protein) or purified human C1q and treated with lipopolysaccharide (LPS: 20ng/ml) Mycobacterium avium 101 (M avium) or ap...
ORGANISM(S): Mus musculus 
2012-03-01 | E-GEOD-35280 | biostudies-arrayexpress
MetabolomicsPFKFB3-mediated glycolysis boosts fibroblast activation and subsequent kidney fibrosis

Renal fibrosis, a hallmark of chronic kidney diseases, is driven by the activation of renal fibroblasts. Recent studies have highlighted the role of glycolysis in this process. Nevertheless, one critical glycolytic activator, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3), remain...

2024-03-12 | MTBLS8281 | MetaboLights
UnknownTrends In Outpatient Mental Health Services Use Before And During The COVID-19 Pandemic.
Not available
S-EPMC9056059 | biostudies-literature
UnknownAcetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Not available
S-EPMC7335356 | biostudies-literature
UnknownFrequency of allogeneic hematopoietic cell transplantation among patients with high- or intermediate-risk acute myeloid leukemia in first complete remission.
Not available
S-EPMC3805928 | biostudies-literature
MetabolomicsA Metabolomic Approach for Predicting Diurnal Changes in Cortisol

INTRODUCTION: The dysregulation of cortisol secretion has been associated with a number of mental health and mood disorders. However, diagnostics for mental health and mood disorders are behavioral and lack biological contexts.

OBJECTIVES: The goal of this ...

2021-09-23 | MTBLS1206 | MetaboLights
UnknownSall1 balances self-renewal and differentiation of renal progenitor cells.
Not available
S-EPMC3929412 | biostudies-literature
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