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TranscriptomicsThe Transcriptome of Utricle Hair Cell Regeneration in the Avian Inner Ear
A comprehensive transcriptome profile of chicken utricle hair cell across a 7 days regenerative time course. Compare gene expression changes in chicken utricle treated with streptomycin to the control. A total of 60 samples were collected from 11 different time points. Each time point contains at le...
ORGANISM(S): Gallus gallus 
2014-04-29 | E-GEOD-57134 | biostudies-arrayexpress
TranscriptomicsChicken versus Quail
Avian beaks show extreme species-specific variability in morphology, though they develop from the same primordial structures. In both humans and birds, cranial neural crest cells are the primary source of mesenchyme for the frontonasal prominence; previous work has shown that these cells contain mol...
ORGANISM(S): Coturnix japonica 
2009-12-02 | E-GEOD-11027 | biostudies-arrayexpress
TranscriptomicsDuck versus Chicken
Avian beaks show extreme species-specific variability in morphology, though they develop from the same primordial structures. In both humans and birds, cranial neural crest cells are the primary source of mesenchyme for the frontonasal prominence; previous work has shown that these cells contain mol...
ORGANISM(S): Anas platyrhynchos 
2009-12-02 | E-GEOD-11028 | biostudies-arrayexpress
TranscriptomicsIntra-species comparisons
Avian beaks show extreme species-specific variability in morphology, though they develop from the same primordial structures. In both humans and birds, cranial neural crest cells are the primary source of mesenchyme for the frontonasal prominence; previous work has shown that these cells contain mol...
ORGANISM(S): Coturnix japonica 
2009-12-02 | E-GEOD-11030 | biostudies-arrayexpress
TranscriptomicsDuck versus Quail
Avian beaks show extreme species-specific variability in morphology, though they develop from the same primordial structures. In both humans and birds, cranial neural crest cells are the primary source of mesenchyme for the frontonasal prominence; previous work has shown that these cells contain mol...
ORGANISM(S): Anas platyrhynchos 
2009-12-02 | E-GEOD-11029 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse discrete microdissected inner ear tissues from E9 to E15 at half-day intervals.
The inner ear in mammals is derived from a simple ectodermal thickening called the otic placode. Through a series of complex morphological changes, the placode forms the mature inner ear comprising of the auditory organ (cochlea) and the vestibular/balance organs (utricle, saccule, and three semi-ci...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7536 | biostudies-arrayexpress
TranscriptomicsA cross-species analysis of microRNAs in the developing avian face
Avian beaks show extreme species-specific variability in morphology, though they develop from the same primordial structures. In both humans and birds, cranial neural crest cells are the primary source of mesenchyme for the frontonasal prominence; previous work has shown that these cells contain mol...
ORGANISM(S): Coturnix japonica 
2012-05-02 | E-GEOD-30716 | biostudies-arrayexpress
TranscriptomicsDissociated avian utricle sensory epithelia treated with one of various siRNAs or small molecule inhibitors
The inner ear utilizes sensory hair cells as mechano-electric transducers for sensing sound and balance. In mammals, these sensory hair cells lack the capacity for regeneration and if damaged lead to hearing or balance disorders. However, non-mammalian vertebrates such as birds maintain their regene...
ORGANISM(S): Gallus gallus 
2010-07-02 | E-GEOD-16842 | biostudies-arrayexpress
UnknownExome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.
Not available
S-EPMC3515204 | biostudies-literature
TranscriptomicsExpression data from proximal, middle, and distal segments of E6.5 chicken cochlea
Precise frequency discrimination is a hallmark of auditory function in birds and mammals. In the cochlea, tuning and spectral separation result from longitudinal differences in basilar membrane stiffness and numerous individual gradiations in sensory hair cell phenotypes, but it is unknown what pat...
ORGANISM(S): Gallus gallus 
2014-04-18 | E-GEOD-56888 | biostudies-arrayexpress
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