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MetabolomicsLow-temperature induced neuro-oxidative stress and metabolic reprogramming in the brain of juvenile fourfinger threadfin (Eleutheronema tetradactylum)
This study investigated the effects of low-temperature stress on the brain metabolome of juvenile fourfinger threadfin (Eleutheronema tetradactylum). Using UHPLC-Q-TOF-MS-based untargeted metabolomics, we analyzed brain tissues from fish exposed to 28°C (control) and 18°C for 7 and 14 days. The aim ...
2026-07-22 | MTBLS15103 | MetaboLights
MetabolomicsMetabolomics-Based Analysis of Adaptive Mechanism of Eleutheronema tetradactylum to Low-Temperature Stress

Temperature is a critical environmental factor influencing fish physiology. Eleutheronema tetradactylum is an economically important warm-water species, but its response to long-term cold stress remains unclear. In this study, we exposed juvenile fish to 18 °C for 7 and 14 days and investigated h...

2026-09-08 | MTBLS15459 | MetaboLights
MetabolomicsMetabolo-transcriptomics analyses reveal alfalfa adaptation to combined saline-alkali and low-temperature stress in the field

Metabolomics analysis revealed specific accumulation of amino acids, organic acids, carbohydrates, fatty acids and flavonoids in ZD compared with that in BM. The core differential metabolites associated with ZD stress resistance included isoleucine, fumaric acid, raffinose and isovitexin. In...

2025-06-19 | MTBLS12611 | MetaboLights
MetabolomicsIntegrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress
OBJECTIVE: Atherosclerotic plaque development is closely associated with the hemodynamic forces applied to endothelial cells (EC). Among these, shear stress (SS) plays a key role in disease development since changes in flow intensity and direction could stimulate an atheroprone or athero...
2019-07-25 | MTBLS739 | MetaboLights
MetabolomicsIonic homeostasis, carbohydrate metabolism, and oxidative balance underlie wild soybean resistance to low potassium stress

The scarcity of potassium resources in farmland soils poses a major challenge to global food security. Wild soybean (Glycine soja), a valuable wild germplasm related to cultivated soybeans, is known for its high-stress resistance and adaptability. This study comprehensively compares two wild soyb...

2025-07-22 | MTBLS12462 | MetaboLights
MetabolomicsPhysiological, Transcriptomic, and Metabolomic Insights into Ammonia-Nitrogen Stress in the Hepatopancreas of Litopenaeus vannamei Acclimated to Low Salinity
High ammonia nitrogen stress markedly decreases the survival rate of Litopenaeus vannamei under low-salinity conditions. Nevertheless, most available studies have primarily focused on the ammonia nitrogen response of small-sized shrimp under single-stressor exposure or normal seawater salinity. The ...
2026-08-13 | MTBLS14736 | MetaboLights
MetabolomicsIntegrated analysis of transcriptome and metabolome reveals molecular responses to ammonia stress in the gills of Litopenaeus vannamei under low-salinity conditions

High ammonia nitrogen stress significantly compromises the survival of Litopenaeus vannamei under low-salinity conditions, posing a common challenge in low-salinity aquaculture. However, existing studies predominantly focus on ammonia nitrogen responses unde...

2026-04-10 | MTBLS14054 | MetaboLights
TranscriptomicsTranscriptional changes in response to oxidative stress in combination with temperature extremes in rice
Genome wide expression profiles of 10-day-old seedlings in response to prior exposure with OS followed by heat stress or cold stress as well simultaneous exposure to OS along with HS/CS was done to study the transcriptional changes in response to combination of stresses. 10-day old rice seedlings we...
ORGANISM(S): Oryza sativa Indica Group 
2012-12-26 | E-GEOD-32704 | biostudies-arrayexpress
MetabolomicsPb Stress and Ectomycorrhizas: Strong Protective Proteomic Responses in Poplar Roots Inoculated with Paxillus involutus Isolate and Characterized by Low Root Colonization Intensity
The commonly observed increased heavy metal tolerance of ectomycorrhized plants is usually linked with the protective role of the fungal hyphae covering colonized plant root tips. However, the molecular tolerance mechanisms in heavy metal stressed low-colonized ectormyocrrhizal plants characterized ...
2022-01-11 | MTBLS1847 | MetaboLights
MetabolomicsMetabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery

Temperature, water and light are 3 abiotic stress factors that have major influences on plant growth, development and reproduction. Plants can be primed by a prior mild stress to enhance their resistance to future stress. We used an untargeted metabolomics approach to examine Arabidopsis thal...

2022-05-30 | MTBLS3672 | MetaboLights
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