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TranscriptomicsIdentification of genes responsive to low-intensity pulsed ultrasound (LIPUS) in MC3T3-E1 preosteoblast cells
Although LIPUS has been shown to enhance fracture healing, the underlying mechanism of LIPUS remains to be fully elucidated. Here, to understand the molecular mechanism underlying cellular responses to LIPUS, we investigated gene expression profiles in mouse MC3T3-E1 preosteoblast cells using a Gene...
ORGANISM(S): Mus musculus 
2013-03-26 | E-GEOD-45487 | biostudies-arrayexpress
ProteomicsThe attenuating effect of low-intensity pulsed ultrasound on hypoxia-induced chondrocyte damage in TMJ osteoarthritis based on TMT labeling quantitative proteomic analysis
Temporomandibular joint osteoarthritis (TMJOA) is a common group of clinical diseases and is an important subtype of temporomandibular joint disorder (TMD). Increased intrajoint pressure or weakened penetration can exacerbate the hypoxic state of the condylar cartilage microenvironment. In this stud...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD026677 | Pride
Hypoxia Tmt labeling proteomics Tmjoa Low-intensity pulsed ultrasound (lipus) Chondrocyte 
TranscriptomicsIdentification of early response genes to low-intensity pulsed ultrasound in bone marrow stromal cells
Low-intensity pulsed ultrasound (LIPUS) has been applied as a therapeutic adjunct to promote fracture healing. However, the detailed molecular mechanisms by which LIPUS promotes bone fracture healing have not yet been fully elucidated. In the present study, the early response genes elicited by low-i...
ORGANISM(S): Mus musculus 
2019-08-19 | GSE135935 | GEO
GenomicsIdentification of early response genes to low-intensity pulsed ultrasound in bone marrow stromal cells
Identification of early response genes to low-intensity pulsed ultrasound in bone marrow stromal cells
PRJNA560688 | ENA
GenomicsOsteocytes as main responders to Low Intensity Pulsed Ultrasound for the treatment of fracture healing
Osteocytes as main responders to Low Intensity Pulsed Ultrasound for the treatment of fracture healing
PRJNA682601 | ENA
GenomicsLow-intensity Pulsed Ultrasound regulates osteoclasts mitochondrial function in the treatment of diabetic periodontitis.
Low-intensity Pulsed Ultrasound regulates osteoclasts mitochondrial function in the treatment of diabetic periodontitis.
PRJNA1179328 | ENA
TranscriptomicsAnti-inflammatory role of low intensity pulsed ultrasound in inhibiting LPS-induced M1 polarization of RAW264.7 via Wnt2b/AXIN/β-catenin
Low-intensity pulsed ultrasound (LIPUS) is a special type of low intensity ultrasound. In periodontal disease, LIPUS was applied as an adjuvant and non-invasive therapeutic treatment. While, the specific mechanism of LIPUS in the treatment of periodontal disease is not quite clear.RAW264.7 cells wer...
ORGANISM(S): Mus musculus 
2024-10-15 | GSE273466 | GEO
GenomicsLow-intensity Pulsed Ultrasound regulates osteoclasts mitochondrial function in the treatment of diabetic periodontitis [scRNA-seq]
Low-intensity Pulsed Ultrasound regulates osteoclasts mitochondrial function in the treatment of diabetic periodontitis [scRNA-seq]
PRJNA1181024 | ENA
GenomicsAnti-inflammatory role of low intensity pulsed ultrasound in inhibiting LPS-induced M1 polarization of RAW264.7 via Wnt2b/AXIN/β-catenin
Anti-inflammatory role of low intensity pulsed ultrasound in inhibiting LPS-induced M1 polarization of RAW264.7 via Wnt2b/AXIN/β-catenin
PRJNA1141980 | ENA
ProteomicsData-independent acquisition proteomics of rat serum between LIPUS and OA
Previous studies have reported that low-intensity pulsed ultrasound (LIPUS) can alleviate cartilage degradation in osteoarthritis (OA). However, the functions and mechanisms of LIPUS in synovial fibrosis with OA require further study. To investigate the role of the PI3K/AKT signaling pathway in syno...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-03-23 | PXD061090 | Pride
Rat  serum  data-independent acquisition proteomics 
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