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TranscriptomicsExpression data from host cells infected with different strains of Toxoplasma gondii
This SuperSeries is composed of the following subset Series: GSE25468: Expression data from Human foreskin fibroblasts (HFFs) infected with Toxoplasma gondii. GSE25469: Expression data from WT or p65-/- mouse embryonic fibroblasts (MEFs) infected with Toxoplasma gondii. Refer to individual Series
ORGANISM(S): Mus musculus 
2011-01-10 | E-GEOD-25476 | biostudies-arrayexpress
TranscriptomicsExpression data from Human foreskin fibroblasts (HFFs) infected with Toxoplasma gondii.
Toxoplasma strains have been shown to modulate host cell transcription. We have found a type II Toxoplasma gene, GRA15, which activates the nuclear translocation of the NF-kappaB p65 transcription factor. We used microarrays to determine how GRA15II modulates host cell transcription. HFFs were infe...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-25468 | biostudies-arrayexpress
TranscriptomicsExpression data from WT or p65-/- mouse embryonic fibroblasts (MEFs) infected with Toxoplasma gondii.
Toxoplasma strains have been shown to modulate host cell transcription. We have found a type II Toxoplasma gene, GRA15, which activates the nuclear translocation of the NF-kappaB p65 transcription factor. We used microarrays to determine how GRA15II modulates host cell transcription, and whether th...
ORGANISM(S): Mus musculus 
2011-01-10 | E-GEOD-25469 | biostudies-arrayexpress
TranscriptomicsATAC-seq data of Amphimedon queenslandica (Demosponge species) through eight developmental stages, from white stage (cleavage) to adult
We report a comprehensive DNA accessibility profile of the Demosponge species Amphimedon queenslandica using Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) through six embryonic developmental stages, a larval stage and adult stage. We assessed the dynamics of chromatin accessi...
ORGANISM(S): Amphimedon queenslandica 
2021-10-10 | E-MTAB-10203 | biostudies-arrayexpress
MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
UnknownInterferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice
Not available
S-SCDT-10_15252-EMBR_202256660 | biostudies-other
MetabolomicsTwo Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System
The biological function of the plant-microbiome system is the result of contributions from the host plant and microbiome members. The Populus root microbiome is a diverse community that has high abundance of β- and γ-Proteobacteria, both classes which include multiple plant-growth promoting represen...
2017-07-25 | MTBLS332 | MetaboLights
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
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