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MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
ProteomicsN-glycopeptide Signatures in AFP-negative HCC
Serum N-linked intact glycopeptides was investigated in AFP-negative HCC and cirrhosis (LC) patients by using label-free quantification methodology.
ORGANISM(S): Homo Sapiens 
2021-01-11 | PXD023500 |
ProteomicsNascent glycoproteome reveal the suppressed expression of glycosylated LAMP2 in response to N-linked glycosylation inhibition
(1) Analysis of newly synthesized proteins under glycosylation inhibition (2) Analysis of newly synthesized glycoproteins during NGI-1 treatment
ORGANISM(S): Homo Sapiens 
PXD028212 |
ProteomicsNascent proteome and glycoproteome reveal the inhibition role of ALG1 in hepatocellular carcinoma cell migration
(1) ALG1-related changes of the nascent proteome in Huh7 cell line (2) Knockdown of ALG1 inhibited the expression of glycosylated N-cadherin
ORGANISM(S): Homo Sapiens 
2021-10-11 | PXD029045 |
ProteomicsN-glycopeptide Signatures in Liver Diseases
(1) A N-glycopeptide method based on 18O/16O C-terminal labelling to obtain comparisons of serum from patients with HBV-related hepatocellular carcinoma (HCC-O18 labelling) and HBV-related liver cirrhosis (LC-O16 labelling) (2) MRM verification of N-glycopeptide alterations
ORGANISM(S): Homo Sapiens 
PXD013586 |
ProteomicsQuantification of intact O-glycopeptides on haptoglobin in sera of patients with hepatocellular carcinoma and liver cirrhosis
In this study, we conducted an intact glycopeptide study on the O-glycosylation of Hp based on mass spectrometry (MS) detection followed by label-free and labeling quantification. Therefore, two main subprojects are included in this project.
ORGANISM(S): Homo Sapiens 
2021-05-28 | PXD023447 |
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