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GenomicsEarly T-helper 1 Differentiation Is Marked by A Follicular Helper-like Transition: Differential Roles of STAT4 and T-bet
Follicular helper T (Tfh) cells comprise an important subset of helper T cells; however, their relationship with other helper lineages is incompletely understood. Herein, we show IL-12 acting via signal transducer and activator of transcription 4 (STAT4) induced both Il21 and Bcl6 genes, generating ...
ORGANISM(S): Mus musculus 
2011-12-27 | E-GEOD-33802 | biostudies-arrayexpress
TranscriptomicsA multiply redundant genetic switch locks in the transcriptional signature of T regulatory cells
This SuperSeries is composed of the following subset Series: GSE40238: Genome-wide maps of FoxP3 binding in transduced CD4+ T cells GSE40273: Gene expression profiling in Treg cells deficient or mutant in candidate FoxP3 cofactors GSE40274: Gene profiling data of CD4+ T cells transduced with FOXP3 a...
ORGANISM(S): Mus musculus 
2012-08-23 | E-GEOD-40278 | biostudies-arrayexpress
GenomicsGenome-wide maps in PDGFB-induced glioma
We performed genome-wide profiling of oligodendrocyte lineage transcription factor 2 (Olig2) and other histone markers in platelet-derived growth factor subunit B (PDGFB)-induced glioma and genome-occupancy analyses coupled with transcriptome profiling to reveal gene regulatory network. Examination ...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-80088 | biostudies-arrayexpress
UnknownDeep learning-based prediction of the T cell receptor-antigen binding specificity.
Not available
S-EPMC9396750 | biostudies-literature
UnknownEnhanced CAR-T activity against established tumors by polarizing human T cells to secrete interleukin-9.
Not available
S-EPMC7677397 | biostudies-literature
TranscriptomicsComparative miRNA Expression Profiles in Individuals with Latent and Active Tuberculosis
To study the role of miRNAs in the transition from latent to active TB and to discover candidate biomarkers that may help predict TB progression, we have employed miRNA microarray expression profiling as a discovery platform to probe the transcriptome of peripheral blood mononuclear cells (PBMCs) wi...
ORGANISM(S): Homo sapiens 
2011-05-10 | E-GEOD-29190 | biostudies-arrayexpress
UnknownATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells.
Not available
S-EPMC11227557 | biostudies-literature
UnknownMultilayer Fluorine-Free MoBTx MBene with Hydrophilic Structural-Modulating for the Fabrication of a Low-Resistance and High-Resolution Humidity Sensor.
Not available
S-EPMC11434212 | biostudies-literature
UnknownCholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment.
Not available
S-EPMC7061417 | biostudies-literature
UnknownGenome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation.
Not available
S-EPMC4975778 | biostudies-literature
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