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ProteomicsProteomic analysis of paclitaxel-tolerant ovarian cancer OVCAR8-Persister cells revealed a metabolic shift to fatty acid oxidation
Human ovarian adenocarcinoma OVCAR8 cells and paclitaxel-induced OVCAR8 -Persister cells (3 biological replicates) were collected in lysis buffer and then sonicated three times on ice. The supernatant represented the whole-cell extract. 4D-data independent acquisition (DIA)-based label-free quantita...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD048089 | Pride
Ovarian cancer Persister cell Fatty acid oxidation Paclitaxel 
TranscriptomicsAyu macrophages at 3.5 hours, 0, 0.5 or 5 ug/ml Leukocyte cell-derived chemotaxin 2 (LECT2), gene expression array, three independent biological replicates
Ayu, Plecoglossus altivelis, is an economically important amphidromous fish species cultured in East Asia. LECT2 is a liver derived cytokine and involved in many pathologic conditions, especially in immune regulation. To understand cellular and molecular mechanisms of LECT2 in immune response of ayu...
ORGANISM(S): Plecoglossus altivelis 
2012-08-21 | E-GEOD-40221 | biostudies-arrayexpress
TranscriptomicsMouse peritoneal macrophages at 3.5 or 48 hours, 0,0.5 or 5 μg/ml Leukocyte cell-derived chemotaxin 2 (LECT2),gene expression array, two independent biological replicates
LECT2 is a liver derived cytokine and involved in many pathologic conditions, especially in immune regulation. To better understand cellular and molecular mechanisms of LECT2 in immune response, mouse peritoneal macrophages were isolated from mouse peritonaeum. After treatment with 0, 0.5 or 5 μg/ml...
ORGANISM(S): Mus musculus 
2011-12-13 | E-GEOD-33721 | biostudies-arrayexpress
ProteomicsMass spectrometry analyzed human IL-33 interaction networks under various stimulations
C-terminal HA tagged hIL-33 were ectopically expressed in HEK293T cells for 24 hours, and demonstrated with indicating stimulations (Ctrl: without stimulations, Pap: 10ug/mL papain exposure for 30min, AS: 0.5mM arsenite exposure for 1hour). Cell lysates were collected for HA-immunoprecipitation and ...
ORGANISM(S): Homo Sapiens 
PXD033460 |
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