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TranscriptomicsHigh-resolution genetic analysis of cancer cell lines with near normal karyotypes
Cancer development is associated with multiple genetic alterations and genomic instability either at the chromosomal or base pair level is generally thought to underlie these changes. However, it is still unknown whether genetic instability is absolutely required for tumorigenesis. Here we investig...
ORGANISM(S): Homo sapiens 
2008-03-14 | E-GEOD-8649 | biostudies-arrayexpress
ProteomicsGPX4 immunoprecipitation in Huh7 cells
Huh7 cells with expression of Flag-GPX4 were treated with IGF1. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Human 
2023-02-22 | MSV000091343 | MassIVE
UnknownA non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
Not available
S-SCDT-10_1038-S44318-024-00104-6 | biostudies-other
ProteomicsiTRAQ-based quantitative proteomic analysis of tobacco leaves in response to cold stress
iTRAQ-based quantitative proteomic analysis was conducted to identified differentially expressed proteins (DEPs) from leaves of one transgenic tobacco line versus the wild type after chilling treatment for 48 h. GO and KEGG enrichment were conducted for analysis of the major biological process, cell...
ORGANISM(S): Nicotiana Tabacum 
2018-11-26 | PXD011822 |
ProteomicsA chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
Through chemical probe screening, we uncovered a novel mechanism of RNA splicing in paclitaxel-resistant TNBC and identified PRMTs as therapeutic targets.
ORGANISM(S): Homo Sapiens 
2024-06-22 | PXD053336 |
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