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We applied a meta-analysis of datasets from seven different microarray studies on lung cancer for differentially expressed genes related to survival time (under 2 y and over 5 y). Systematic bias adjustment in the datasets was performed by distance-weighted discrimination (DWD). We identified a gene...
ORGANISM(S): Homo sapiens 
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
With the widespread of drug-resistant Mycobacterium tuberculosis (Mtb), anti-TB drugs with novel structures and targets are urgently needed to prevent the prevalence of drug-resistant strains. For the past few decades, many Mtb CYPs been structurally and functionally characterized, and some of them ...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2024-03-10 | PXD045505 | Pride
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), continues to be a public health threat. With the development and widespread of drug-resistant TB, the pressure of prevention and treatment is increasing. To determine and quantify the modified proteins, high resolution mass spec...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2023-03-09 | PXD035802 | Pride
Different digestion methods and extraction detergents were examined for membrane proteome sample preparation, and label-free quantitative proteome analysis of the polymyxin B induced Acinetobacter baumannii ATCC 19606 membrane proteome were performed based on nano LC-MS/MS.
ORGANISM(S): Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 
2021-09-13 | PXD026714 | Pride
The increasing spread of drug-resistant bacterial strains presents great challenges to clinical antibacterial treatment and public health, particularly with regard to β-lactamase-producing Enterobacteriaceae. A rapid and accurate detection method that can expedite precise clinical diagnosis and rati...
ORGANISM(S): Klebsiella pneumoniae ATCC BAA-2146 
2022-06-08 | PXD028791 | Pride
Despite surgical treatment of stage I non-small cell lung cancer (NSCLC), one third of patients will eventually have a recurrence. Robust prognostic markers are required to better manage therapy options. MicroRNAs play important roles in human cancers. The purpose of this study is to identify miRNA ...
ORGANISM(S): Homo sapiens 
In plants, transposons and non-protein-coding repeats are epigenetically silenced by CG and non-CG methylation. This pattern of methylation is mediated in part by small RNAs and two specialized RNA polymerases, Pol IV and Pol V, in a process called RNA-directed DNA methylation. By contrast, many pr...
ORGANISM(S): Arabidopsis thaliana 
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