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MetabolomicsUltraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model
This study aims to identify biomarkers for evaluating the therapeutic efficacy of mesalazine on ulcerative colitis by metabolomics and lipidomics. A dextran sulfate sodium-induced mouse model was used. The disease status was assessed by a disease activity index, the TNF-α level of colon was measured...
2022-10-24 | MTBLS2111 | MetaboLights
UnknownRegulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Not available
S-EPMC3962686 | biostudies-literature
UnknownCharacterization of JsWOX1 and JsWOX4 during Callus and Root Induction in the Shrub Species Jasminum sambac.
Not available
S-EPMC6526479 | biostudies-literature
UnknownXPF expression and its relationship with the risk and prognosis of colorectal cancer.
Not available
S-EPMC7789628 | biostudies-literature
MetabolomicsOsh2 mediates Candida resistance to miltefosine by regulating zymosterol transport
Miltefosine has been identified for its antifungal properties, yet the mechanisms underlying its action and the development of resistance remain unclear. In this study, we induced drug resistance in various Candida species through concentration gradient exposure, successfully obtaining a miltefosine...
2025-07-03 | MTBLS12270 | MetaboLights
TranscriptomicsGenome-wide analysis reveals dynamic changes in microRNAs expression during vascular cambium development in Chinese fir
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that play key roles in the process of plant development. To date, extensive studies of miRNAs have been performed in a few model plants, but few efforts have focused on small RNAs in conifers because of the lack of reference sequences for these ...
ORGANISM(S): Cunninghamia lanceolata 
2015-04-07 | E-GEOD-53933 | biostudies-arrayexpress
TranscriptomicsGenome-Wide binding sites of two MADS-domain transcription factors SOC1 and SVP in Arabidopsis during the floral transition
The floral transition in Arabidopsis is tightly controlled by complex genetic regulatory networks in response to endogenous and environmental flowering signals. SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) and SHORT VEGETATIVE PHASE (SVP), two key MADS-domain transcription factors, perceive the...
ORGANISM(S): Arabidopsis thaliana 
2012-02-01 | E-GEOD-33297 | biostudies-arrayexpress
TranscriptomicsHuman Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
We generated induced human hepatocyte by transduction of several lineage specific transcription factors and analyzed the gene expression profile of generated hepatocytes and freshly isolated human hepatocytes through RNA sequencing. Global gene expression profile analysis
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-54066 | biostudies-arrayexpress
MetabolomicsFecal metabolomic study in patients with choledocholithiasis concurrent with cholangitis

Metabolites associated with the gut microbiota play an important role in the pathogenesis of choledocholithiasis concurrent with cholangitis (CC). This study aims to characterize the fecal metabolite profile of CC patients and to investigate the correlation and balance within the gut cross-domain...

2025-08-11 | MTBLS12772 | MetaboLights
TranscriptomicsAffymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary
To identify such targets of leukemia-related miRNAs such as miR-196b, we conducted Affymetrix gene arrays of leukemic BM samples from 24 mice including 9 primary (including 3 each of negative control, MLL-AF9, and miR-196b+MLL-AF9) and 15 secondary (including 3 negative control, 6 MLL-AF9, and 6 miR...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-34185 | biostudies-arrayexpress
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