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ProteomicsOptogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan
Despite longstanding scientific interest in the centrality of mitochondria to biological aging, directly controlling mitochondrial function to test causality has eluded researchers. We show that specifically boosting mitochondrial membrane potential through a light-activated proton pump reversed age...
ORGANISM(S): Caenorhabditis elegans 
2022-11-11 | PXD033901 | Pride
C. elegans Aging 
Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
ProteomicsAnalyzing Bioactive Effects of the Minor Hop Compound Xanthohumol C on Human Breast Cancer Cells Using Quantitative Proteomics
We provide label-free data-dependent acquisition proteomics data of mcf-7 breast cancer cell lines treated with the pure minor hop compounds xanthohumol and xanthohumol c.
ORGANISM(S): Homo sapiens (Human) 
2019-03-05 | PXD010785 | Pride
Cancer Minor hop compounds Mcf-7 Xanthohumol c Human Lc-ms/ms Bioactivity 
UnknownThe sea cucumber Holothurialineata Ludwig, 1875 (Holothuroidea, Aspidochirotida, Holothuriidae) re-described from the newly found type.
Not available
S-EPMC6477819 | biostudies-literature
UnknownInhibition of tenascin C rescues abnormally reduced Na currents in dystrophin-deficient ventricular cardiomyocytes.
Not available
S-EPMC7618084 | biostudies-literature
UnknownThe Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.
Not available
S-EPMC4882431 | biostudies-literature
ProteomicsIdentification of a novel xanthan-binding module of a multi-modular Cohnella sp. xanthanase
A new strain of xanthan-degrading bacteria identified as Cohnella sp. has been isolated from a xanthan thickener for food production. The strain was able to utilize xanthan as the only carbon source and reduce the viscosity of the xanthan-containing medium during cultivation. Xanthan hydrolytic acti...
ORGANISM(S): Cohnella sp. 
2024-06-14 | PXD050379 | Pride
Cbm66 Cohnella Xanthan-binding module Xanthanase Xanthan Mobility shift 
ProteomicsComparative proteomics of meat-spoiling bacteria predicts drivers for their coexistence on modified atmosphere packaged meat
Oxygen and carbon dioxide are common protective gases used in modified atmosphere packaging (MAP) of meat. Within the package, they selectively suppress members of the spoilage microbiome, reshaping it to adapted species concomitantly growing upon MAP. Thus, this species must exhibit adaptation mech...
ORGANISM(S): Leuconostoc gelidum subsp. gelidum Carnobacterium maltaromaticum Leuconostoc gelidum subsp. gasicomitatum Carnobacterium divergens Brochothrix thermosphacta 
2020-02-05 | PXD016382 | Pride
Differential proteomics Carnobacterium divergens Leuconostoc gelidum subsp. gelidum Brochothrix thermosphacta Leuconostoc gelidum subsp. gasicomitatum Carnobacterium maltaromaticum Meat-spoiling bacteria 
GenomicsGenome of C. kroppenstedtii subsp. demodicis
Genome of C. kroppenstedtii subsp. demodicis
PRJEB60059 | ENA
ProteomicsA twin xanthan lyase-dependent xanthan degradation system in Paenibacillus taichungensis I5
Xanthan gum, a natural heteropolysaccharide produced by Xanthomonas species, has many biotechnological applications across industries due to its unique rheological properties. Expanding its utility requires specific enzymes capable of targeted xanthan modification or degradation. In this study, a no...
ORGANISM(S): Paenibacillus taichungensis 
2026-02-02 | PXD068698 | Pride
Xanthanase Gene cluster Paenibacillus taichungensis Xanthan gum Xanthan lyase 
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