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UnknownInternal transcribed spacer as effective molecular marker for the detection of natural hybridization between the bivalves Pinna nobilis and Pinna rudis.
Not available
S-EPMC11347391 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of sorted Tfh cells from C57BL/6 Foxp3-GFP mice immunized with OVA-IFA and OVA-CpG
The aim of the project was the identification of the transcriptional signature of Tfh cells that emerge following immunization with different adjuvants. For this purpose C57Bl/6 mice, bearing a Foxp3-GFP reporter system, were immunized with OVA-IFA or OVA-CpG. At day 11 post-immunization, Foxp3 nega...
ORGANISM(S): Mus musculus 
2023-07-31 | E-MTAB-12085 | biostudies-arrayexpress
UnknownGαi2+ vomeronasal neurons govern the initial outcome of an acute social competition.
Not available
S-EPMC6972791 | biostudies-literature
ProteomicsNeddylation inhibition halts acetaminophen induced liver injury boosting anabolic cardiolipin pathway
Drug Induced-liver injury (DILI) is a significant cause of acute liver failure (ALF) and liver transplantation in the Western world. APAP overdose is a main contributor of DILI, leading to hepatocyte cell death through necrosis. Herein, we identified that neddylation, an essential post-translational...
ORGANISM(S): Mus Musculus 
PXD053221 |
TranscriptomicsSubtractive Hybridization Reveals Novel Genes Associated with D. melanogaster Early Embryogenesis.
Background: The early stages of D. melanogaster embryogenesis involve cell migration and pattern formation, and lead to the formation of three germ layers (the ectoderm, mesoderm and endoderm). These developmental events are controlled by differential gene activity. In the current study we used a su...
ORGANISM(S): Drosophila melanogaster 
2010-05-16 | E-GEOD-15000 | biostudies-arrayexpress
ProteomicsDevelopment of a high-throughput (10 minute microflow gradient) platform for quantitation of histone modifications on a new QTOF instrument
Histone post-translational modifications (PTMs) regulate gene expression patterns through epigenetic mechanisms. The 5 histone proteins (H1, H2A, H2B, H3, and H4) are extensively modified, with over 75 distinct modification types spanning more than 200 sites. Despite strong advances in mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-06 | MSV000094696 | MassIVE
ProteomicsDevelopment of a high-throughput (10 minute microflow gradient) platform for quantitation of histone modifications on a new QTOF instrument
Histone post-translational modifications (PTMs) regulate gene expression patterns through epigenetic mechanisms. The 5 histone proteins (H1, H2A, H2B, H3, and H4) are extensively modified, with over 75 distinct modification types spanning more than 200 sites. Despite strong advances in mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-06 | MSV000094695 | MassIVE
UnknownA multi-tissue study of immune gene expression profiling highlights the key role of the nasal epithelium in COVID-19 severity.
Not available
S-EPMC8861187 | biostudies-literature
ModelsFanconi anemia and checkpoint recovery
The FA/BRCA pathway repairs DNA interstrand crosslinks. Mutations in this pathway cause Fanconi anemia (FA), a chromosome instability syndrome with bone marrow failure and cancer predisposition. Upon DNA damage, normal and FA cells inhibit the cell cycle progression, until the G2/M checkpoint is tur...
4790 | Cell Collective
UnknownCharacterisation of the blood RNA host response underpinning severity in COVID-19 patients.
Not available
S-EPMC9288817 | biostudies-literature
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