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TranscriptomicsTranscription profiling of juman HTM cell line transfected by triplicate with microRNA 29b or scramble control to investigate changes in gene expression induced by miR29b in HTM cells
To investigate the role of miR-29b on the changes in expression of genes involved in the synthesis and deposition of extracellular matrix in human trabecular meshwork cells (HTM). Experiment Overall Design: One HTM cell line was transfected by triplicate with microRNA 29b or scramble control. After...
ORGANISM(S): Homo sapiens 
2010-01-19 | E-GEOD-18713 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human trabecular meshwork cultured cells, non-glaucomatous and POAG tissue
The goal of this study was to contrast genome-wide gene expression profiles of cultured human trabecular meshwork (HTM) cells, to that of control and primary open angle glaucoma (POAG) HTM tissues. Total RNA from cultured HTM cells and HTM tissue dissected from control and POAG anterior segments fix...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4316 | biostudies-arrayexpress
TranscriptomicsChanges in Gene expression mediated by Cyclic Mechanical Stress in Trabecular Meshwork Cells
Purpose: To investigate the changes in gene expression induced by cyclic mechanical stress (CMS) in trabecular meshwork (TM) cells. Methods: HTM cultures from three donors were plated on type I collagen-coated flexible silicone bottom plates and subjected to 15% stretching, 1 cycle per second for 6...
ORGANISM(S): Homo sapiens 
2009-03-04 | E-GEOD-14768 | biostudies-arrayexpress
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