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UnknownEfficacy of Fecal Microbiota, Live-jslm (REBYOTA®), Among Patients Exposed to Non-Clostridioides difficile Infection Antibiotics: Post Hoc Subgroup Analysis of a Phase 2 Open-Label Study.
Not available
S-EPMC11244191 | biostudies-literature
UnknownRationale and Design of VOYAGER: Long-term Outcomes of Faricimab and Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema in Clinical Practice.
Not available
S-EPMC10831184 | biostudies-literature
TranscriptomicsMulti-omic analysis resolves coordinated immune responses to mild, moderate and severe COVID-19
This study utilizes multi-omic biological data to perform deep immunophenotyping on the major immune cell classes in COVID-19 patients. 10X Genomics Chromium Single Cell Kits were used with Biolegend TotalSeq-C human antibodies to gather single-cell transcriptomic, surface protein, and TCR/BCR seque...
ORGANISM(S): Homo sapiens 
2020-10-29 | E-MTAB-9357 | biostudies-arrayexpress
TranscriptomicsMultiple Early Factors Anticipate Post-Acute COVID-19 Sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk-factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2...
ORGANISM(S): Homo sapiens 
2022-02-01 | E-MTAB-10129 | biostudies-arrayexpress
ProteomicsCalcium-loaded acylated segment controls the membrane penetration capacity of repeats-in-toxin cytolysins
Loading of calcium ions into the numerous carboxy-terminus-proximal binding sites in the Repeats in ToXin (RTX) domains drives the cooperative and vectorial folding of RTX β-roll structures involved in cell binding and membrane penetration of RTX cytolysins. Two additional binding sites for calcium ...
ORGANISM(S): Bordetella pertussis NBRC 107857 Escherichia coli Bacteria 
2026-04-28 | PXD065966 | Pride
Adenylate cyclase toxin Calcium binding sites Rtx toxin Folding 
ProteomicsProximal proteome and ubiquitination landscape of E3 Ubiquitin Ligase Mindbomb 1
To characterize the proximal proteome of Mindbomb 1 (MIB1) during adenovirus (AdV) infection ?we performed proximity labeling. MIB1 KO cell lines generated in the Hap1 cell line were stably reconstituted with either WT MIB1-APEX2, the MIB1 ubiquitination-defective mutant C985S-APEX2 or APEX2-mKate. ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020542 | Pride
Apex2 Adenovirus Mindbomb 1 Lfq Tubes 
ProteomicsProteomic Remodeling During Tumor Cell-Induced Platelet Aggregation Unveils Metastatic Drivers in Colorectal Cancer
Colorectal cancer (CRC) is frequently associated with metastasis, resulting in high mortality rates. Platelets are known to play a crucial role in the metastatic cascade influencing tumor microenvironment remodeling, promoting cell transformation, facilitating metastatic niche formation, and shieldi...
ORGANISM(S): Homo sapiens (Human) 
2026-04-02 | PXD062043 | Pride
Tcipa Proteomics Emt Dia-ms Platelets Metastasis Colorectal cancer 
UnknownAdult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus.
Not available
S-EPMC6800071 | biostudies-literature
UnknownTissue-resident memory CD8 T cell diversity is spatiotemporally imprinted.
Not available
S-EPMC11903307 | biostudies-literature
UnknownStructured training program on confocal laser endomicroscopy for pancreatic cystic lesions: a multicenter prospective study among early-career endosonographers (with video).
Not available
S-EPMC10771632 | biostudies-literature
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