Lung squamous cell carcinoma

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Unknown (3381)
Transcriptomics (644)
Genomics (477)
Clinical (117)
Proteomics (69)
Other (10)
Methylation profiling (6)
Genomic (4)
Metabolomics (4)

Organisms

Homo sapiens (614)
Mus musculus (141)
Andropogon gerardi (47)
Bacteria (47)
Canis lupus familiaris (47)
Chromatiales bacterium OalgGamma1 (47)
Clavibacter nebraskensis NCPPB 2581 (47)
Cnidaria (47)
Ensifer adhaerens (47)
Fasciola (47)
Human alphaherpesvirus 1 strain 17 (47)
Human alphaherpesvirus 1 strain KOS (47)
Rattus norvegicus (7)
Mytilus galloprovincialis (3)
Schizophyllum commune (2)
Gallus gallus (2)
synthetic construct (2)
Capra hircus (1)
Streptococcus mutans UA159 (1)
Phaeodactylum tricornutum (1)
Aspergillus fumigatus (1)
Bacillus subtilis (1)
Oncorhynchus mykiss (1)
Bos taurus (1)
Ovis aries (1)
Escherichia coli (1)
Sus scrofa (1)
Danio rerio (1)
human gammaherpesvirus 4 (1)
Cancer (1)

Organisms

Homo sapiens (261)
Mus musculus (51)
unidentified (1)
human lung metagenome (1)

Repository

biostudies-arrayexpress (480)
ENA (360)
geo (261)
pride (47)
EGA (26)
MassIVE (12)
ExpressionAtlas (11)
iProX (7)
dbGaP (4)
MetaboLights (4)
jPOST (3)
EVA (1)

Tissue

Lung (27)
Uterine cervix (4)
Breast (4)
Esophagus (4)
Stomach (4)
Pancreas (4)
Ovary (4)
Uterus (4)
Urinary bladder (4)
Prostate gland (4)
Brain (4)
Liver (4)
Kidney (4)
Skin (4)
Blood (4)
Large intestine (3)
Skeletal muscle tissue (3)
Thyroid gland (3)
Mouth mucosa (2)
Adrenal gland (2)
Testis (2)
Nasal septum (1)
Cartilage tissue (1)
Chordate pharynx (1)
Oral cavity (1)
Pleura (1)
Tongue (1)
Musculature (1)
Hematopoietic system (1)
Peripheral nervous system (1)

Disease

Non-small cell lung carcinoma (12)
Lung adenocarcinoma (9)
Head and neck squamous cell carcinoma (8)
Squamous cell lung carcinoma (7)
Breast adenocarcinoma (7)
Squamous cell carcinoma (7)
Pancreatic adenocarcinoma (6)
Gastric adenocarcinoma (6)
Hepatocellular carcinoma (6)
Ovarian adenocarcinoma (6)
Melanoma (6)
Renal cell carcinoma (6)
Cervical adenocarcinoma (5)
Cervical squamous cell carcinoma (5)
Prostate adenocarcinoma (5)
Cholangiocarcinoma (5)
Large cell lung carcinoma (4)
Ovarian carcinoma (4)
Follicular thyroid carcinoma (4)
Lymphoma (4)
Bladder transitional cell carcinoma (4)
Invasive lobular carcinoma (4)
Glioma (4)
Esophageal adenocarcinoma (4)
Colon carcinoma (3)
Anaplastic astrocytoma (3)
Chondrosarcoma (3)
Mesothelioma (3)
Diffuse large B-cell lymphoma (3)
Acute myeloid leukemia (3)

Technology Type

Mass Spectrometry (47)
Shotgun proteomics (26)
Affinity purification coupled with mass spectrometry proteomics (8)
Bottom-up proteomics (7)
Data-dependent acquisition (5)
Mass spectrometry (4)
SWATH MS (3)
Gel-based experiment (2)
Illumina HiSeq 2000, ILLUMINA, Affymetrix SNP 6.0 (1)
Infinium_OmniExpress-24v1.0 (1)
Illumina HiSeq 2000, ILLUMINA (1)
Data-independent acquisition (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (17)
N/A (6)
NextSeq 500 (5)
Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, (4)
Illumina HiSeq 2500 (4)
10X Genomics reagent kit (3)
10X Chromium Nuclei Isolation Kit (2)
Illumina NovaSeq X (2)
Illumina HiSeq 4000 (2)
STAR v2.5.3a, rpkmforgenes, RSeQC 2.6.1 (1)
Illumina Nextera XT index kits (Set A–D) (1)
Oligo(dT) primer and SuperScript II reverse transcriptase (ThermoFisher Scientific), TapeStation 4200 or 2100 Bioanalyzer with a DNA High Sensitivity chip (Agilent Biotechnologies) (1)
Aria III (BD Biosciences) (1)
Chromium Next GEM Single Cell Multiome Reagent Bundle (1)
10X Genomics reagents (1)
Single cells were captured using the 10x Genomics Chromium Controller. (1)
10X Chromium On-Chip Multiplex (1)
Agilent 2100 bioanalyzer (1)
NanoDrop ND-1000 (1)
Axon Instruments GenePix 4000B scanner (1)
Affymetrix GeneChip Scanner 3000 7G (1)
Illumina HiScanSQ (1)
Illumina Genome Analyzer IIx (1)
G2505A DNA microarray scanner [Agilent] (1)
Axon- GenePix4000B (1)
HiSeq X Ten (1)
Illumina NextSeq 500 (1)
Illumina HiSeq 1500 (1)
NextSeq 550 (1)
Illumina HiSeq 2000 (1)

Publication Date

2015 (69)
2013 (67)
2014 (65)
2011 (62)
2012 (61)
2026 (52)
2010 (49)
2016 (46)
2025 (40)
2020 (39)
2008 (38)
2009 (37)
2019 (31)
2021 (27)
2018 (25)
2024 (24)
2023 (22)
2017 (19)
2022 (18)
2007 (16)
2005 (7)
2006 (6)
2004 (1)

CHEBI ID

CHEBI:194570 (1)
CHEBI:194568 (1)
CHEBI:66237 (1)
CHEBI:194564 (1)
CHEBI:89130 (1)
CHEBI:194562 (1)
CHEBI:176770 (1)
CHEBI:194560 (1)
CHEBI:186951 (1)
CHEBI:194571 (1)
CHEBI:194569 (1)
CHEBI:194567 (1)
CHEBI:194565 (1)
CHEBI:194563 (1)
CHEBI:194561 (1)
CHEBI:89706 (1)
CHEBI:78745 (1)
CHEBI:176044 (1)
CHEBI:189014 (1)
CHEBI:34128 (1)
CHEBI:194566 (1)
CHEBI:186351 (1)
CHEBI:170591 (1)
CHEBI:171768 (1)
CHEBI:190405 (1)
CHEBI:175838 (1)
CHEBI:179993 (1)
CHEBI:180382 (1)
CHEBI:89681 (1)
CHEBI:86102 (1)

Metabolite Name

TMC-1D (1)
PKODiA-PC (1)
19-(3-methyl-butanoyloxy)-villanovane-13alpha,17-diol (1)
PC(16:0/5:0(COOH)) (1)
PS(DiMe(11,3)/DiMe(11,5)) (1)
DG(14:0/19:0/0:0) (1)
Americine (1)
Postin (1)
Chenodeoxycholic acid sulfate (1)
Simvastatin hydroxy acid (1)
3beta-(3-methyl-butanoyloxy)-villanovane-13alpha,17-diol (1)
Cadaverine (1)
Deoxycholic acid glycine conjugate (1)
3b,12a-Dihydroxy-5a-cholanoic acid (1)
Lithocholyltaurine (1)
D-Biotin (1)
Agmatine (1)
Gamma-Linolenic acid (1)
PE(18:0/20:5(5Z,8Z,11Z,14Z,17Z)) (1)
LysoPE(0:0/22:1(13Z)) (1)
1-Oleoylglycerophosphoserine (1)
PS(15:0/22:1(13Z)) (1)
PE(O-18:0/0:0) (1)
PE(O-18:1(9Z)/0:0) (1)
PA(14:1(9Z)/14:0) (1)
Dynorphin B (6-9) (1)
Gentamicin (1)
Allolithocholic acid (1)
FAD (1)
Dehydroepiandrosterone sulfate (1)

First Public Date

2014 (64)
2026 (44)
2024 (36)
2025 (35)
2020 (25)
2015 (23)
2023 (22)
2018 (22)
2019 (20)
2021 (19)
2017 (18)
2022 (16)
2013 (11)
2016 (4)
2011 (1)

Modification

2x(15)N labeled L-lysine (2)
4x(15)N labeled L-arginine (2)

Study status

Recruiting (45)
Completed (35)
Active, not recruiting (16)
Terminated (11)
Withdrawn (3)
Not provided (3)
Not yet recruiting (3)
Enrolling by invitation (1)

Study type

Transcription profiling by array (308)
Comparative genomic hybridization by array (33)
RNA-seq of coding RNA (23)
ChIP-seq (13)
RNA-seq of coding RNA from single cells (13)
Methylation profiling by array (11)
Unknown experiment type (7)
ChIP-chip by array (7)
Genotyping by array (7)
RNA-seq of non coding RNA (7)
Transcription profiling by RT-PCR (6)
MicroRNA profiling by array (5)
Methylation profiling by high throughput sequencing (5)
Other (4)
Single nucleus RNA sequencing (4)
Transcription profiling by SAGE (3)
DNA-seq (3)
RNA-seq of total RNA (3)
ChIP-chip by tiling array (2)
Cell line - One-color microarray (2)
Human - One-color microarray (2)
Cell line - High-throughput sequencing (2)
RNA-seq of non coding RNA from single cells (1)
Animal - One-color microarray (1)
One-color microarray (1)
High-throughput sequencing (1)
Transcription profiling by tiling array (1)
ATAC-seq (1)
RIP-seq (1)
ScATAC-seq (1)

Release Date

2024 (567)
2022 (451)
2023 (342)
2021 (329)
2025 (322)
2020 (298)
2019 (212)
2016 (186)
2018 (181)
2017 (168)
2015 (152)
2014 (146)
2013 (107)
2012 (92)
2011 (79)
2010 (61)
2009 (44)
2008 (42)
2026 (41)
2007 (18)
2005 (8)
2006 (6)
2004 (4)
2002 (2)
2001 (1)
1998 (1)

Lab affiliation

Moffitt Cancer Center (3)
Washington University in St. Louis (3)
Merck & Co., Inc. (2)
Molecular Oncology Chemical Biology and Molecular Medicine Moffitt Cancer Center (2)
1, Department of Biology, Institute of Molecular Systems Biology, ETH, Zurich, Switzerland 2, Faculty of Science, University of Zurich, Zurich, Switzerland (1)
1Cancer Institute, the Second Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310029, China 2Cancer Center, Zhejiang University, Hangzhou 310058, China 3Research Center for Life Science and Human Health, Binjiang Institute of Zhejiang University, Hangzhou 310053, China (1)
Calico Life Sciences (1)
Center for Biomedical Mass Spectrometry Boston University School of Medicine 670 Albany St, Rm 511 Boston, MA 02118-2646 USA (1)
Centre for Proteomic Research B85, Life Sciences Building University of Southampton University Road Highfield Southampton, Hants. SO17 1BJ United Kingdom (1)
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA, 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge MA, 02139, USA; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge MA, 02139, USA (1)
Department of Biology, Technion–Israel Institute of Technology Haifa, Israel (1)
Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark (1)
Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, United States. (1)
Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, United States of America (1)
Department of Gametes and Embryo Biology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences (1)
Department of Gametes and Embryo Biology, Institute of Animal Reproduction and Food Research Polish Academy of Sciences, Olsztyn, 10-748, Poland (1)
Department of Medicinal Chemistry, University of Michigan (1)
Department of Medicine II, Hematology/Oncology, Goethe University, Germany German Cancer Research Center and German Cancer Consortium, Germany (1)
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel (1)
Department of Otorhinolaryngology, University Hospital Essen, Essen, Germany (1)
Department of Thoracic Surgery and Lung Transplantation, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China (1)
Group of Immunoproteomics Medical Research Center (MFZ) University Hospital Essen Hufelandstraße 55 D-45147 Essen, Germany (1)
Hospital for Sick Children, Toronto, Ontario, Canada (1)
Institute of Bioinformatics , International Technology Park, Bangalore, India (1)
Institute of Bioinformatics , International Technology Park, Bangalore, India. (1)
Institute of Bioinformatics, Bangalore, Karnataka, India (1)
Institute of Bioinformatics, ITPB, Bangalore, India (1)
Institute of Chemical Technologies and Analytics, TU Wien, Getreidemarkt 9, 1060 Vienna, Austria; Research and Diagnostic Institute of Pathology, Medical University of Graz, Stiftingtalstraße 6, 8036, Graz, Austria (1)
Institute of Pathology and Molecular Pathology, University Hospital Zurich, Switzerland (1)
Lab Head and Scientist D, Jubilee Centre for Medical Research, JMMC&RI, Kerala, India (1)

Location

United States (91)
Spain (21)
France (17)
United Kingdom (17)
Italy (16)
Australia (16)
Germany (15)
Belgium (11)
Canada (11)
Japan (10)
Taiwan (9)
Netherlands (8)
South Korea (8)
China (6)
Poland (6)
Israel (5)
Denmark (4)
Austria (4)
Oceania (3)
Georgia (3)
Singapore (3)
Asia except Japan (3)
Europe (3)
North America (3)
Chile (3)
Czechia (3)
Switzerland (3)
Hong Kong (2)
Norway (2)
Puerto Rico (2)

Keyword

Pembrolizumab (25)
Nivolumab (12)
Immunotherapy (12)
HNSCC (7)
SCCHN (7)
EGFR (7)
CRC (7)
Carboplatin (6)
Ipilimumab (6)
Paclitaxel (6)
Cetuximab (6)
Atezolizumab (5)
Albumin-Bound Paclitaxel (4)
PD-1 (4)
RCC (4)
TNBC (4)
IL-2 (4)
Gemcitabine (4)
Trastuzumab (4)
Antibodies, Monoclonal (4)
Spartalizumab (4)
Bevacizumab (4)
Cell therapy (3)
PTPN11 (3)
Urothelial Cancer (3)
Renal Cell Cancer (3)
Gastroesophageal Junction Cancer (3)
EGFR Positive (3)
EGFR+ (3)
Triple Negative Breast Cancer (3)

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Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients

There is large variability among lung squamous cell carcinoma (SCC) patients in response to treatment with cisplatin based chemotherapy. LncRNAs is potentional a new type of predictive marker that can identify subgroups of patients who benefit from chemotherapy and it will have great value for treat...

ORGANISM(S): Homo sapiens

2015-05-18 | E-GEOD-59245 | biostudies-arrayexpress

Human lung squamous cell carcinoma expression profiling

Lung squamous cell carcinoma gene expression (LSCC) is highly variable. This study discovered and validated LSCC gene expression subtypes. RNA from tumors and a common reference were hybridized to Agilent two color microarrays

ORGANISM(S): Homo sapiens

2010-08-06 | E-GEOD-17710 | biostudies-arrayexpress

Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells

Lung squamous cell carcinoma (SCC) is a deadly disease for which current treatments are inadequate. We demonstrate that bi-allelic inactivation of Lkb1 and Pten in the mouse lung led to SCC that recapitulated the histology, gene expression and microenvironment found in human disease. Lkb1/Pten-null ...

ORGANISM(S): Mus musculus

2014-01-24 | E-GEOD-54351 | biostudies-arrayexpress

Quantitative proteomic analysis of lung adenocarcinoma and squamous cell carcinoma primary tissues using high resolution mass spectrometry

Lung cancer is the leading cause of preventable death globally and is broadly classified into adenocarcinoma and squamous cell carcinoma depending upon cell type. In this study, we carried out mass spectrometry based quantitative proteomic analysis of lung adenocarcinoma and squamous cell carcinoma ...

ORGANISM(S): Homo sapiens (Human)

2018-10-02 | PXD008700 | Pride

Expression profiling defines a recurrence signature in lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is about 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent disease. Conventional prognostic markers are unable to determine which patients with completely resected disea...

ORGANISM(S): Homo sapiens

2010-07-01 | E-GEOD-5123 | biostudies-arrayexpress

SOX2 is a new oncogene activated by the recurrent 3q26.3 amplifications in lung Squamous Cell Carcinoma

This SuperSeries is composed of the following subset Series: GSE14859: ArrayCGH mapping of chromosome 3 aberrations in lung Squamous Cell Carcinoma (SCC) GSE14883: SOX2 overexpression effect on human lung squamous cells GSE15079: ArrayCGH mapping of the recurrent 3q26.3-q27mplifications in lung Squa...

ORGANISM(S): Homo sapiens

2010-05-14 | E-GEOD-15080 | biostudies-arrayexpress

ArrayCGH mapping of chromosome 3 aberrations in lung Squamous Cell Carcinoma (SCC)

To prospectively identify new oncogenes implicated in lung Squamous Cell Carcinoma pathogenesis, we investigated chromosome 3 aberrations in advanced tumours using arrayCGH. These aberrations are indeed among the most frequent aberrations in lung SCC and correlate with SCC patient's poor prognosis. ...

ORGANISM(S): Homo sapiens

2010-05-14 | E-GEOD-14859 | biostudies-arrayexpress

DNA copy number variation profiling and transcription profiling by array of 93 human lung squamous cell carcinoma samples

The basaloïd carcinoma (pure) and the basaloïd variant of lung squamous cell carcinoma (SCC) have a dismal prognosis but their underlying specific molecular characteristics remain obscure. This experiment uses DNA copy number aberrations and mRNA expression pangenomic profiles of 93 SCC, including ...

ORGANISM(S): Homo sapiens

2014-10-03 | E-MTAB-1727 | biostudies-arrayexpress

Gene expression profiles of two lung squamous cell carcinoma cell lines treated with SOX2 siRNA

SOX2 is a transcription factor essential for self-renewal and pluripotency of embryonic stem cells. Recently SOX2 was found overexpressed in the majority of the lung squamous cell carcinoma (SQC), in which it acts as a lineage-survival oncogene. However, downstream targets/pathways of SOX2 in lung S...

ORGANISM(S): Homo sapiens

2014-07-30 | E-GEOD-48871 | biostudies-arrayexpress

Human- lung squamous cell carcinoma LC-MS/MS Orbitrap Fusion

Integration of LC-MS/MS data links biological processes to fragmentation of tumor epithelia, and morphological marker that associates with decreased patient survival in lung squamous cell carcinoma

ORGANISM(S): Homo sapiens (Human)

2017-05-15 | PXD006132 | Pride

Human Lung squamous cell carcinoma Fusion

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4714 Results

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