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MetabolomicsTidal filtering drives microbiome assembly and metabolic coupling in desiccation-tolerant red algae


This study investigates how the intertidal red alga Pyropia haitanensis (Bangiophyceae) achieves rapid desiccation-rehydration tolerance through coordinated interactions between the host, its associated microbiome, and key metabolites. By integrating 16S rRNA amplicon sequencing, metag...

2026-05-07 | MTBLS13613 | MetaboLights
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
GenomicsProfiling Genome-wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells
We have engineered the chromatin-modifying apparatus and formulated a novel technology, termed Clickable Chromatin Enrichment with parallel DNA sequencing (CliEn-seq), to probe genome-wide chromatin modification within living cells. Examine (E)-hex-2-en-5-ynylation mediated by engineered G9a Y1154A ...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-42792 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders.
Expression profiling of lymphoblast cell lines of autisms from Simons Simplex Families. This experiment aims to utilize blood expression data to study the functional impact and to prioritize rare variants potentially associated with autism. Total RNA obtained from lmyphoblast cell lines derived from...
ORGANISM(S): Homo sapiens 
2012-05-04 | E-GEOD-37772 | biostudies-arrayexpress
ProteomicsGlmS plays a key role in the virulence and biofilm formation ability of Staphylococcus aureus promoted by advanced glycation end products
Staphylococcus aureus (S. aureus) is well known for its biofilm formation ability and is responsible for serious, chronic refractory infections worldwide. We previously demonstrated that advanced glycation end products (AGEs), a hallmark of chronic hyperglycemia in diabetic tissues, enhanced biofilm...
ORGANISM(S): Staphylococcus aureus 
2024-05-22 | PXD046076 | Pride
Staphylococcus aureus  advanced glycation end products  biofilm formation  glms-sigb regulatory axis 
UnknownEffects of Polysaccharide Supplementation on Lactic Acid Bacteria-Fermented Soy Protein Gel: Structural Characteristics, Allergenicity, and Epitope Analysis.
Not available
S-EPMC11854590 | biostudies-literature
UnknownInsights into Binding Mechanisms of Potential Inhibitors Targeting PCSK9 Protein via Molecular Dynamics Simulation and Free Energy Calculation.
Not available
S-EPMC12298945 | biostudies-literature
TranscriptomicsSystematic reconstruction of molecular cascades regulating growth plate development using single-cell RNA-seq
The growth plate, which comprises sequentially differentiated cell layers, is a critical structure for bone elongation and regeneration. Although several key regulators in growth plate development have been identified using primarily genetic perturbation, the systematic understanding is still limite...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-76157 | biostudies-arrayexpress
UnknownTransmissibility of the variant of concern for SARS-CoV-2 in six regions.
Not available
S-EPMC11168441 | biostudies-literature
UnknownCorrelation between mumps and meteorological factors in Xiamen City, China: A modelling study.
Not available
S-EPMC9062423 | biostudies-literature
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