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TranscriptomicsTranscriptional profiling of human in vitro primed Th1, Th2, Th9 and Treg T cells
To test whether human in vitro primed Th9 cells recapitulate the core pathogenic Th2 cell phenotype, we differentiated naïve T cells into Th1 (IL-12), Th2 (IL-4), Th9 (IL-4+TGF-β), and iTreg (TGF-β). After 7 days transcriptomic profiling by bulk RNA-seq was performed.
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12199 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of human IL-9R+ T helper cells in presence of recombinant IL-9 against untreated control
To study the effect of paracrine interleukin-9 (IL-9) on T helper cells, we incubated IL-9R+ T helper cells isolated from blood (5 samples) and skin (3 samples) with or without IL-9 for 12h and the transcriptome was analyzed by bulk RNA-seq.
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12204 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of human Th9 T cell clones treated with GW9662 against untreated control
To investigate the role of PPAR-γ in human TH cells, transcriptional response of activated “TH9” clones to treatment with GW9662, a potent PPAR-γ antagonist was assessed. “TH9” cell clones were incubated with GW9662 for 48h and activated with αCD3/2/28 for 12 h. Transcriptomic profiling was performe...
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12197 | biostudies-arrayexpress
GenomicsT cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T cell lymphomas
Analysis of T cell receptor and clonal architecture in T cell lymphoma
PRJEB72787 | ENA
UnknownCharacterization of the effect of histone deacetylation inhibitors on CD8+ T cells in the context of aging.
Not available
S-EPMC9682763 | biostudies-literature
UnknownUtilization of point-of-care tests among general practitioners, a cross-sectional study.
Not available
S-EPMC8906527 | biostudies-literature
UnknownDivergent Effects of EZH1 and EZH2 Protein Expression on the Prognosis of Patients with T-Cell Lymphomas.
Not available
S-EPMC8698684 | biostudies-literature
UnknownT cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort.
Not available
S-EPMC10258752 | biostudies-literature
UnknownMicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell-mediated cytolysis.
Not available
S-EPMC9887093 | biostudies-literature
UnknownThe mineralocorticoid receptor leads to increased expression of EGFR and T-type calcium channels that support HL-1 cell hypertrophy.
Not available
S-EPMC8225817 | biostudies-literature
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