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MetabolomicsBupleurum chinense DC polysaccharides ameliorate DSS-induced ulcerative colitis by regulating gut microbiota and tryptophan metabolism via NF-κB pathway

Background: Bupleurum chinense DC polysaccharide (BCP) demonstrates a significant role in ameliorating gastric ulceration and enhancing intestinal barrier function, and have broad medicinal value. Nevertheless, the therapeutic effects and mechanisms in ulcerative colitis (UC) remain to be elucida...

2026-02-01 | MTBLS13814 | MetaboLights
UnknownHnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Not available
S-EPMC5355122 | biostudies-literature
UnknownAnalysis of Postsurgical Health-Related Quality of Life and Quality of Voice of Patients With Laryngeal Carcinoma.
Not available
S-EPMC4706258 | biostudies-literature
UnknownA novel BaEVRless-LV packaging system for the production of lentiviral vectors for clinical-grade CAR-NK cell manufacturing.
Not available
S-EPMC11899593 | biostudies-literature
UnknownStructural basis of selective cannabinoid CB2 receptor activation.
Not available
S-EPMC10017709 | biostudies-literature
ProteomicsSarcomeric Proteoform Landscape in Ischemic Cardiomyopathy Defined by Top-down Proteomics
In ischemic cardiomyopathy (ICM), left ventricular systolic dysfunction leads to reduced blood flow and oxygen supply to the heart. Alterations in sarcomeric protein function and expression play prominent roles in the onset and progression of cardiomyopathies; however, the molecular mechanisms under...
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD038066 | Pride
Ischemic cardiomyopathy Top-down proteomics Sarcomere Z-disk proteins Myofilament proteins Quantitative proteomics Human heart proteomics 
UnknownTemporal trends in hyperuricaemia among adults in Wuhan city, China, from 2010 to 2019: a cross-sectional study.
Not available
S-EPMC8016088 | biostudies-literature
UnknownDevelopment of SSR markers and identification of major quantitative trait loci controlling shelling percentage in cultivated peanut (Arachis hypogaea L.).
Not available
S-EPMC5511596 | biostudies-literature
MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
UnknownStable QTLs for Plant Height on Chromosome A09 Identified From Two Mapping Populations in Peanut (Arachis hypogaea L.).
Not available
S-EPMC5982159 | biostudies-literature
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