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ProteomicsProteomic and Phosphoproteomic Sequencing of NRK-49F Cells after TGF-β1 Stimulation: Impact of USP7 Knockout
Dysregulation of the expression of ubiquitin - specific protease 7 (USP7) has been associated with tumor progression. However, the biological functions and clinical significance of USP7 in renal fibrosis remain insufficiently explored. In this study, proteomic and phosphoproteomic sequencing were pe...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-07 | PXD059829 | Pride
Nrk-49f usp7 
UnknownGenotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.
Not available
S-EPMC7439928 | biostudies-literature
GenomicsGenome-wide maps of Foxa2 binding sites in mouse embryonic stem cell-derived definitive endoderm cells
Foxa2 is required for endoderm differentiation into hepatic lineage. The mechanism of activation for Foxa2 during this developmental process has not been elucidated yet. We established an in vitro system to guide ES cells differentiating into definitive endoderm (DE) cells and the following DE cells...
ORGANISM(S): Mus musculus 
2012-08-29 | E-GEOD-40423 | biostudies-arrayexpress
ProteomicsComprehensive analysis of individual variation in the urinary proteome revealed significant gender differences
To elucidate the individual variation and related factors influencing the urinary proteome, we comprehensively analyzed the urine samples from healthy adult donors (aged 20-69 years). Co-expression network analysis revealed protein clusters representing the metabolic status, gender-related differenc...
ORGANISM(S): Homo Sapiens 
2019-05-21 | PXD013949 |
ProteomicsUSP5 Stabilizes YTHDF1 to Control Cancer Immune Surveillance through mTORC1-mediated Phosphorylation
The N6-methyladenosine (m6A) binding protein YTHDF1 emerges as a frequently upregulated oncogene across various cancer types. Its depletion significantly improves the efficacy of cancer immune checkpoint blockade (ICB) treatment. A comprehensive understanding of the molecular mechanisms governing YT...
ORGANISM(S): Homo Sapiens 
2024-11-14 | PXD057917 |
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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