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TranscriptomicsMicroarray analysis of splenic reservoir monocytes and their blood counterparts
A current paradigm states that monocytes circulate freely and patrol blood vessels, but differentiate irreversibly into dendritic cells or macrophages upon tissue entry. Here we show that bona fide undifferentiated monocytes reside in the spleen and outnumber their equivalents in circulation. The re...
ORGANISM(S): Mus musculus 
2009-08-02 | E-GEOD-14850 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human memory T cells stimulated with Phl p-extract in healthy and allergic individuals
Differential transcriptional response of memory T cells stimulated with Phl p-extract in healthy and allergic individuals.
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-243 | biostudies-arrayexpress
TranscriptomicsCombined inhibition of TGFM-NM-2 and PDGF signaling attenuates radiation-induced pulmonary fibrosis
To investigate effects on mRNA expression in mouse lung tissue through treatment with Ly, Su, Imatinib, irradiation and combinations of them. mRNA expression was measured 24 days after irradiation. 2 biological replicates were analyzed for each treatment condition (control, Ly, Imatinib, Su, Ly+Imat...
ORGANISM(S): Mus musculus 
2015-01-15 | E-GEOD-65011 | biostudies-arrayexpress
TranscriptomicsMYC is a major determinant of mitotic cell fate
Purpose: To determine global gene expression changes following siRNA knockdown of Myc, Kcnk1, and Snta1 compared to non-targeting siRNAs or mock-transfected cells Methods: Total RNA was processed using the Illumina TruSeq Stranded mRNA Sample Preparation Kit according to manufacturer’s protocol. Gen...
ORGANISM(S): Homo sapiens 
2015-07-13 | E-GEOD-68219 | biostudies-arrayexpress
UnknownDiscovery of novel Schistosoma japonicum antigens using a targeted protein microarray approach.
Not available
S-EPMC4080988 | biostudies-literature
TranscriptomicsExpression data from Pseudomonas aeruginosa (wild type and lasRrhlR mutant strains) exposed to human neutrophils
In the present in vitro study, interactions between P. aeruginosa (sessile biofilms as well as planktonic cells) and PMNs were analyzed by means of DNA microarray based transcriptomics. We found that the P. aeruginosa wild type biofilms, in contrast to planktonic cultures and quorum sensing (QS) def...
ORGANISM(S): Pseudomonas aeruginosa 
2009-08-04 | E-GEOD-6769 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pancreas from rats of four strains after drinking ethanol at various concentrations for twelve months
Male rats from one of four strains (Wistar, AA, HAD or P) were housed individually in standard hanging rodent cages (Ehret, Emmendingen, Germany) on a 12-hour light-dark cycle with lights on at 07:00 a.m.. Animals were provided with food (Sniff, Soest, Germany), tap water, 5, 10 and 20% (v/v) ethano...
ORGANISM(S): Rattus norvegicus 
2009-12-31 | E-MEXP-776 | biostudies-arrayexpress
UnknownCullin-3 regulates late endosome maturation.
Not available
S-EPMC3271891 | biostudies-literature
UnknownHistidine is selectively required for the growth of Myc-dependent dedifferentiation tumours in the <i>Drosophila</i> CNS.
Not available
S-EPMC6443203 | biostudies-literature
TranscriptomicsDevelopment pathway for skin resident memory CD103+CD8+ T cells
Tissue resident memory T cells (TRM) provide superior protection against infection localised to extra-lymphoid compartments in the body. Here we show that CD103+CD8+ TRM cells develop in skin from killer cell lectin-like receptor (KLR)G1-negative precursors that selectively infiltrate the epithelia...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-47045 | biostudies-arrayexpress
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