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TranscriptomicsExpression data from Human CD40L+ Tcells
To assess the nature of CD8+CD40L+ memory Tcells, we compared the gene expression to CD8+CD40L- and CD4+ counterparts, and found similarities in expression of genes encoding cytokines PBMCs were isolated from five healthy donors. The cells were stimulated with PMA/Ionomycin for 6 h, and subsequently...
ORGANISM(S): Homo sapiens 
2013-08-05 | E-GEOD-44126 | biostudies-arrayexpress
UnknownThe inactivation of the Niemann Pick C1 cholesterol transporter restricts SARS-CoV-2 entry into host cells by decreasing ACE2 abundance at the plasma membrane.
Not available
S-EPMC11662611 | biostudies-literature
UnknownPatient-identified priorities for a mental health program tailored to premenstrual dysphoric disorder.
Not available
S-EPMC12166257 | biostudies-literature
ProteomicsQuantitative proteomic study of two cervical cancer cell lines upon re-expression of Galectin 7
Galectin-7 expression was found to be strongly reduced in cervical cancer cell lines. The same tumor cell lines in which Galectin-7 was ectopically expressed exhibited significant decrease in their tumorigenic capacity in vitro and in vivo. The proteomic changes in the cervical cancer cell lines HeL...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080855 | MassIVE
TranscriptomicsHIT analysis of T cells activated in the presence of TGF-β
We have developed a multi-analyte fluid-phase protein array technology termed high-throughput immunophenotyping using transcription (HIT). This method employs a panel of monoclonal antibodies, each tagged with a unique oligonucleotide sequence that serves as a molecular barcode. After staining a s...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10762 | biostudies-arrayexpress
TranscriptomicsTrancriptome analysis of peripheral leukocytes from SARS-CoV-2 infected patients and healthy uninfected individuals during the first wave of COVID-19 pandemic in Brazil
To evaluate the gene expression profiling of peripheral leukocytes in different outcomes of SARS-CoV-2 infections, whole blood samples were collected from individuals with positive SARS-CoV-2 nasopharyngeal swab by RT-PCR (54 patients) and healthy uninfected individuals (12 volunteers). Infected pat...
ORGANISM(S): Homo sapiens 
2022-04-29 | E-MTAB-11240 | biostudies-arrayexpress
UnknownNorth American COVID-19 ST-Segment-Elevation Myocardial Infarction (NACMI) registry: Rationale, design, and implications.
Not available
S-EPMC7229476 | biostudies-literature
TranscriptomicsDifferentially regulated circulating microRNAs in post-menopausal women suffering from osteoporotic femoral-neck fractures
Osteoporosis is the consequence of altered bone metabolism resulting in the systemic reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) regulate gene expression on a post-transcriptional level are known to take part in the control of bone formation and bone reso...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-60230 | biostudies-arrayexpress
TranscriptomicsMicroRNAs differentially present in the plasma of HIV elite controllers
Elite controllers maintain HIV-1 viral loads below the limit of detection. The mechanisms responsible for this phenomenon are poorly understood. As microRNAs (miRNAs) are regulators of gene expression and some of them modulate HIV infection, we have studied the miRNA profile in plasma from HIV elite...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-58868 | biostudies-arrayexpress
TranscriptomicsExpression data of LNCaP and MDA PCa 2b cells in absence or presence of IL6
Prostate cancer (PCa) development and progression are associated with chronic inflammation. The cytokine interleukin (IL)-6 can influence progression, differentiation, survival, and angiogenesis of PCa. To identify novel pathways that are triggered by IL-6, we performed a gene expression profiling o...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-47973 | biostudies-arrayexpress
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