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MetabolomicsDesorption electrospray ionisation mass spectrometry imaging of esophageal lymph mode metastases
Lymph node metastases (LNM) and primary tumour samples were analysed using desorption electrospray ionisation mass spectrometry imaging (DESI MSI). Current assessment of LNM depends on subjective histopathological assessment, whereas analysis by DESI MSI permits an entirely objective assessment. The...
2017-01-10 | MTBLS385 | MetaboLights
MetabolomicsSimultaneous targeting of PD-1 and IL2Rβγ with radiation therapy to inhibit pancreatic cancer growth and metastasis - mouse spleen and lymph node T-cell metabolomics
Not available
ORGANISM(S): Mus musculus 
ST002487 | MetabolomicsWorkbench
TranscriptomicsGene Expression Profiling of Fixed Tissues of Lymph Node Metastasis in Hepatocellular Carcinoma
RNA was extracted from formalin-fixed specimens of paired intratumoral and peritumoral tissues of patients with lymph node-positive (n=20) or negative (n=20) HCC. A cDNA-mediated annealing, selection, extension, and ligation assay was performed with an array of 502 known cancer-related genes to iden...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-GEOD-28248 | biostudies-arrayexpress
TranscriptomicsImmune and tumor cell gene expression from node positive and node negative breast cancers' primary tumor, lymph nodes and peripheral blood
Analysis of purified immune and breast tumor cells from three major compartments where cancer and immune cells interact: primary tumor, tumor draining lymph nodes (tumor invaded or tumor free), and peripheral blood. The results suggests that node-positive patients’ immune regulation and functionali...
ORGANISM(S): Homo sapiens 
2013-01-11 | E-GEOD-41986 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.
An experiment was performed to investigate the perservation of gene expression upon metastasis of primary head and neck squamous cell carcinomas to the cervical lymph node.
ORGANISM(S): Homo sapiens 
2006-10-23 | E-TABM-114 | biostudies-arrayexpress
TranscriptomicsDecreased expression of key tumour suppressor microRNAs is associated with lymph node metastases in triple negative breast cancer
Breast cancer is the most common malignancy that develops in women, responsible for the highest cancer-associated death rates. Triple negative breast cancers (TNBC) represent an important subtype that have an aggressive clinical phenotype, are associated with a higher likelihood of metastasis and ar...
ORGANISM(S): Homo sapiens 
2014-11-24 | E-GEOD-38167 | biostudies-arrayexpress
TranscriptomicsComparison of lymph node negative (N0) and lymph node metastasis (N+) head and neck squamous-cell carcinomas (HNSCC)
A classifier was build on 82 training samples to differentiate between lymph node negative (N0) and lymph node metastasis (N+) head and neck squamous-cell carcinomas (HNSCC). The 102 predictor genes that resulted from this classifier where then validated against a independent validation set.
ORGANISM(S): Homo sapiens 
2005-01-09 | E-UMCU-11 | biostudies-arrayexpress
ProteomicsiTRAQ proteomics of sentinel lymph nodes for the identification of extra cellular matrix protein signatures that can flag metastasis in early breast cancer
Background Breast cancer patients who present in the early stage of disease are affected by metastasis to the axillary group of lymph nodes. The first among this group that is affected is called as sentinel lymph node, and metastasis to this lymph node is crucial for the staging of cancer and the qu...
ORGANISM(S): Homo sapiens (Human) 
2022-05-01 | PXD027668 | Pride
Itraq proteomics Extracellular matrix proteins Early breast cancer Sentinel lymph node metastasis 
TranscriptomicsGenome-wide methylation analysis of esophageal squamous cell carcinoma
Genome-wide methylation analysis was performed by methylated DNA immunoprecipitation-CGI microarray analysis. A pool of four cancer samples without lymph node metastasis, two pools of four cancer samples with lymph node metastasis, and three metastatic lymph nodes were prepared from the patients, an...
ORGANISM(S): Homo sapiens 
2010-12-21 | E-GEOD-21238 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymph node (sinuses) and tonsil (no sinuses) to identify signature genes that are prime candidates for mediating adhesion of tumor cells to sinusoidal cells
Lymph node vs. tonsil
ORGANISM(S): Homo sapiens 
2007-09-12 | E-GEOD-2665 | biostudies-arrayexpress
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