Sort   by:  
 Page size 
GenomicsIdentifying genetic consequences of Epstein-Barr Virus transformation by comparing an individual’s genomic DNA with that of its lymphoblastoid cell line.
A detailed analysis of whole genomes can be now achieved with next generation sequencing. Epstein Barr Virus (EBV) transformation is a widely used strategy in clinical research to obtain an unlimited source of a subject’s DNA. Although the mechanism of transformation and immortalization by EBV is re...
EGAS00001000323 | EGA
Transcriptomicssmall RNA-sequencing of 452 lymphoblastoid cell lines from the 1000 Genomes
This RNA sequencing data set of 465 human lymphoblastoid cell line samples from the CEU, FIN, GBR, TSI and YRI populations from the 1000 Genomes sample collection was created by the Geuvadis consortium (www.geuvadis.org, http://www.geuvadis.org/web/geuvadis/our-rnaseq-project). The data is under emb...
ORGANISM(S): Homo sapiens 
2012-11-06 | E-GEUV-2 | biostudies-arrayexpress
GenomicsAHR ChIP-seq in lymphoblastoid cell line
AHR ChIP-seq in lymphoblastoid cell line
PRJNA479757 | ENA
TranscriptomicsTranscription profiling of human lymphoblastoid cell lines that are part of the NIHPDR exposed to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) to identify novel predictors of resistance to DNA damaging agents
We have investigated whether gene expression signatures can be used to predict inter-individual responses to DNA damaging agents; We used microarrays to detail inter-individual variation in gene expression across a healthy population under basal and damage induced conditions Experiment Overall Desig...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-10313 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 287 lymphoblastoid cell lines
We used microarrays to identify the variation of basal gene expression level among 287 lymphoblastoid cell lines. Radiation therapy is used to treat half of all cancer patients. Response to radiation therapy varies widely among patients. Therefore, we performed a genome-wide association study (GWA...
ORGANISM(S): Homo sapiens 
2010-07-24 | E-GEOD-23120 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing and small RNA-sequencing of 465 lymphoblastoid cell lines from the 1000 Genomes
This RNA sequencing data set of 465 human lymphoblastoid cell line samples from the CEU, FIN, GBR, TSI and YRI populations from the 1000 Genomes sample collection was created by the Geuvadis consortium (www.geuvadis.org, http://www.geuvadis.org/web/geuvadis/our-rnaseq-project). The data is under emb...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEUV-3 | biostudies-arrayexpress
TranscriptomicsVariability of gene expression profiles in human blood and lymphoblastoid cell lines
Readily accessible samples such as peripheral blood or cell lines are increasingly being used in large cohorts to characterise gene expression differences between a patient group and healthy controls. However, cell and RNA isolation procedures and the variety of cell types that make up whole blood c...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-30916 | biostudies-arrayexpress
TranscriptomicsThe viral and cellular microRNA targetome in lymphoblastoid cell lines
Epstein-Barr virus (EBV) is a human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-41437 | biostudies-arrayexpress
TranscriptomicsEpstein Barr virus Nuclear Antigen 3C regulated genes in Lymphoblastoid Cell Lines
Epstein Barr virus (EBV) nuclear antigen 3C (EBNA3C) is an essential transcription factor for initiating and maintaining human B lymphocyte transformation to lymphoblastoid cell lines (LCLs). To comprehensively identify EBNA3C regulated cell genes in LCLs, oligonucleotide arrays were used to compare...
ORGANISM(S): Homo sapiens 
2011-01-06 | E-GEOD-24362 | biostudies-arrayexpress
TranscriptomicsExpression in lymphoblastoid cell lines following hydrogen peroxide bolus at 5 times
The general expression profile in human lymphoblastoid cell lines treated with 9 uM, 90 uM or 900 uM bolus of hydrogen peroxide at 0, 4,12,24, and 48 hours. Four cell lines (GM07055, GM14569, GM14467, and 12057) were treated separately and total RNA was pooled in equal amounts prior to labeling and...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-21800 | biostudies-arrayexpress
Sort   by:  
 Page size