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TranscriptomicsGlobal gene expression profiles in ovarian cancer linked to Lynch syndrome
Heredity is a major cause of ovarian cancer. Lynch syndrome is associated with 10-12% risk of ovarian cancer, diagnosis at young age and a predilection for endometrioid and clear cell tumors. Global gene expression profiling applied to 25 Lynch syndrome-associated and 42 sporadic ovarian cancers rev...
ORGANISM(S): Homo sapiens 
2013-10-14 | E-GEOD-37394 | biostudies-arrayexpress
GenomicsMSI analysis of Lynch syndrome urothelial cancers
MSI analysis of Lynch syndrome urothelial cancers
PRJEB58093 | ENA
GenomicsUrine MSI analysis to detect Lynch syndrome urothelial cancer
Urine MSI analysis to detect Lynch syndrome urothelial cancer
PRJEB85932 | ENA
TranscriptomicsGenomic profiling of colorectal cancer from patients with Lynch syndrome and Familial colorectal cancer type X with comparison to sporadic microsatelite stable and instable colorectal cancer
Lynch syndrome and Familial colorectal cancer type X (FCCTX) are clinically diagnosed using the same criteria, but genomic differences exist between these two groups and the genomic profiles share similarities with their sporadic counterparts, mismatch repair (MMR) deficient and proficient tumors, r...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-38405 | biostudies-arrayexpress
GenomicsMolecular analysis of cancer genomes in children with Lynch syndrome: exploring causal associations
Molecular characterization of 20 tumors of 18 children with Lynch syndrome to investigate causality. This characterization includes the investigation of second hits, tumor mutational load, mutational signatures and MMR protein expression.
EGAS00001006992 | EGA
GenomicsLynch Syndrome Targeted Metagenome
Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neoplasia ( AAS-Lynch-Microbiote)
PRJEB70919 | ENA
GenomicsMolecular subtype classification of urothelial carcinoma in Lynch syndrome
Molecular subtype classification of urothelial carcinoma in Lynch syndrome
PRJNA414169 | ENA
GenomicsGut microbiome in Lynch syndrome patients
Metagenomics of the mucosal and stool microbiome in Lynch syndrome
PRJNA526861 | ENA
GenomicsImmune Profiling of Premalignant Lesions in Patients with Lynch Syndrome
Immune Profiling of Premalignant Lesions in Patients with Lynch Syndrome
PRJNA417076 | ENA
GenomicsMolecular analysis of cancer genomes in children with Lynch syndrome: exploring causal associations
Lynch syndrome (LS) predisposes to cancer in adulthood and is caused by heterozygous germline variants in a mismatch repair (MMR) gene. Recent studies show an increased prevalence of LS among children with cancer, suggesting a causal relationship. For LS-spectrum (LSS) cancers, including high-grade ...
EGAS00001007146 | EGA
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