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MetabolomicsCeramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma
Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...
2023-12-20 | MTBLS7649 | MetaboLights
GenomicsOncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication.
ChIP-sequencing reads from Oncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication, accepted to PLOS Pathogens
ORGANISM(S): Homo sapiens 
2016-06-01 | E-MTAB-4356 | biostudies-arrayexpress
TranscriptomicsCapture-C identification of chromatin interactions of 53 selected cellular loci prior to and post induction of EBV's lytic cycle in Raji cells
Identification of specific chromatin interactions of 53 selected genes with the Capture-C technique in Raji iBZLF1 cells prior to and 6 or 15 h after induction of EBV’s lytic cycle. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7825 | biostudies-arrayexpress
ProteomicsProteomics of EBV-infected lytic and refractory cells
Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...
ORGANISM(S): Homo sapiens (Human) 
2016-04-27 | PXD001838 | Pride
Proteomic analysis Epstein-barr virus Lytic activation 
Proteomics,MultiomicsProteomics of EBV-infected lytic and refractory cells
Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079993 | MassIVE
ProteomicsProteome analyses define marked differences between N. caninum isolates throughout the tachyzoite lytic cycle
Neospora caninum has been recognised as the main cause of transmissible abortion in cattle worldwide. Although the pathogenesis of this disease remains largely unknown, different factors associated to both the host and the parasite have influence in the dynamics of the disease. Intraspecific variati...
ORGANISM(S): Primates Neospora caninum (Coccidian parasite) 
2017-11-17 | PXD007062 | Pride
Tachyzoite Lytic cycle Virulence. Neospora 
TranscriptomicsEpstein–Barr virus (EBV) Rta-mediated cell cycle arrest enables permissive replication of EBV and Kaposi’s sarcoma-associated herpesvirus in 293 cells
Epstein-Barr virus (EBV) Rta is a latent-lytic molecular switch evolutionarily conserved in all gamma-herpesviruses. In previous studies, doxycycline-inducible Rta was shown to potently produce an irreversible G1 arrest followed by cellular senescence in 293 cells. Here, we demonstrate that in this ...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-24587 | biostudies-arrayexpress
GenomicsOncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication.
Oncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication.
PRJEB12546 | ENA
ProteomicsiTRAQ-based Phosphoproteomic Analysis of Toxoplasma gondii Tachyzoites at the lytic cycle of just invading and prior to egress
The invasion and egress are the two key steps in T. gondii lytic cycle that are vital to the propagation of its infection, and the phosphorylation is believed to play important roles in these processes. In this study, we performed phosphoproteomic analysis of these two dynamic processes in the lytic...
ORGANISM(S): Toxoplasma Gondii Rh 
PXD020655 |
GenomicsUnderstanding differential expression of genes during EBV lytic cycle reactivation by employing high throughput RNA-sequencing
Understanding differential expression of genes during EBV lytic cycle reactivation by employing high throughput RNA-sequencing
PRJNA995436 | ENA
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