Sort   by:  
 Page size 
ProteomicsMetabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen
Cancer cells depend on mitochondria to sustain their increased metabolic needs therefore, mitochondria constitute an interesting target for cancer treatment. We recently developed novel small-molecule inhibitors of mitochondrial transcription (IMTs) that selectively target mitochondrial gene express...
ORGANISM(S): Homo sapiens (Human) 
2021-11-11 | PXD026481 | Pride
Mtdna Cancer Crispr-cas9 genetic screen Inhibitor of mitochondrial transcription Chemoresistance 
TranscriptomicsExtrinsic and Intrinsic Regulation of DOR/TRP53INP2 Expression in Mice
The objective is to relate changes in expression of DOR/TRP53INP2, a factor involved in thyroid hormone action and autophagy, to body composition in mice fed a fat (FD) or high fat diet (HFD) for 8 days and in a genetically obese mouse model. We conclude that DOR expression depends on sex, fat conte...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-32872 | biostudies-arrayexpress
Sort   by:  
 Page size