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ProteomicsLyve-1 deficiency plasma proteomics
Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding hyaluronan, LYVE-1 mediates adhesion of leukocytes and cancer cells to endothelial cells. Here, we analyzed the impact of LYVE-1 on physiolog...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD032717 | Pride
Hepatic immune microenvironment Liver metastasis Lyve-1 Liver homeostasis Plasma 
TranscriptomicsInvestigation of the gene expression profile of LYVE-1-positive macrophages
LYVE-1-positive macrophages were observed to be closely spatially associated with the developing lymphatic vasculature. The role of this population of macrophages in the embryo is uncharacterised. We used microarray analyses to investigate which genes are differentially regulated between LYVE-1-posi...
ORGANISM(S): Mus musculus 
2010-10-02 | E-GEOD-24492 | biostudies-arrayexpress
GenomicsDifferential gene set analysis of isolated liver sinusoidal endothelial cells of Lyve-1 deficient (Lyve-1-KO) and control mice
Differential gene set analysis of isolated liver sinusoidal endothelial cells of Lyve-1 deficient (Lyve-1-KO) and control mice
PRJNA818200 | ENA
GenomicsProfiling of murine resident adipose tissue and aortic macrophages according to their expression status of LYVE-1
Profiling of murine resident adipose tissue and aortic macrophages according to their expression status of LYVE-1
PRJNA472001 | ENA
TranscriptomicsInvestigation of the gene expression profile of LYVE-1-positive macrophages
LYVE-1-positive macrophages were observed to be closely spatially associated with the developing lymphatic vasculature. The role of this population of macrophages in the embryo is uncharacterised. We used microarray analyses to investigate which genes are differentially regulated between LYVE-1-posi...
ORGANISM(S): Mus musculus 
2010-10-02 | GSE24492 | GEO
GenomicsLYVE-1-expressing macrophages modulate the extracellular matrix in the mammary gland and contribute to mammary tumor growth
LYVE-1-expressing macrophages modulate the extracellular matrix in the mammary gland and contribute to mammary tumor growth
PRJNA1008238 | ENA
TranscriptomicsProfiling of murine resident adipose tissue and aortic macrophages according to their expression status of LYVE-1
Beside their role in conventional immune regulation, macrophages are now recognised as essential regulator of local tissue homeostasis depending on the tissue in which they reside. Using phenotyping, we found that LYVE-1+ macrophages are the major resident macrophage population in murine aorta and a...
ORGANISM(S): Mus musculus 
2018-06-01 | GSE114630 | GEO
TranscriptomicsLYVE-1-expressing macrophages modulate the extracellular matrix in the mammary gland and contribute to mammary tumor growth
Macrophages represent a heterogeneous myeloid population with diverse functions in normal tissues and tumors. While LYVE-1 macrophages have been identified in stromal regions of the normal mammary gland and mammary tumor, their functions in these regions remain unknown. Using a genetic LYVE-1+ macro...
ORGANISM(S): Mus musculus 
2024-06-05 | GSE241469 | GEO
UnknownHyaluronan and LYVE-1 and allograft function in lung transplantation recipients.
Not available
S-EPMC6588572 | biostudies-literature
TranscriptomicsDifferential gene set analysis of isolated liver sinusoidal endothelial cells of Lyve-1 deficient (Lyve-1-KO) and control mice
Liver sinusoidal endothelial cells (LSEC) of both Lyve-1-KO (B6.129S1-Lyve1tm1Lhua/J (JAX stock #006221)) and Ctrl mice were isolated and mRNA were comparatively analyzed by a microarray (Affimetryx). Even though there was no single gene significantly dysregulated, an overall representation analysis...
ORGANISM(S): Mus musculus 
2022-12-14 | GSE199055 | GEO
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