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GenomicsArhodomonas aquaeolei strain:M3R-1517
Arhodomonas aquaeolei strain:M3R-1517 Genome sequencing and assembly
PRJNA873797 | ENA
UnknownAutoantibodies against the Second Extracellular Loop of M3R Do neither Induce nor Indicate Primary Sjogren's Syndrome.
Not available
S-EPMC4765836 | biostudies-literature
UnknownAbsence of toxin gene transfer from Clostridioides difficile strain 630Δerm to nontoxigenic C. difficile strain NTCD-M3r in filter mating experiments.
Not available
S-EPMC9242483 | biostudies-literature
UnknownDivergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia.
Not available
S-EPMC4021221 | biostudies-literature
OtherIdentification of M3 muscarinic acetylcholine receptor reactive Th17 cells in patients with primary Sjögren’s syndrome
Previously M3 muscarinic acetylcholine receptore (M3R) reactive Th1 cells were identified, and here, M3R reactive Th17 cells were identified in peripheral blood of primary Sjögren’s syndrome patients using ELISpot method. To assess TCR repertoire overlap between identified M3R reactive Th17 cells, a...
ORGANISM(S): Homo sapiens 
2021-04-18 | GSE148966 | GEO
TranscriptomicsSelective modulation of murine intestinal M1 and M3 muscarinic receptor expression has divergent effects on specialized epithelial cells and body weight
M1 and M3 muscarinic receptors encoded by CHRM1 and CHRM3 mediate neuronal and non-neuronal cholinergic signaling. Mice with global M3R deficiency reportedly weigh less than controls, but the cell type(s) involved are unknown. As the intestinal epithelium modulates nutrient absorption, we asked if d...
ORGANISM(S): Mus musculus 
2026-01-16 | GSE316547 | GEO
TranscriptomicsEpithelial Muscarinic Receptor 3 Ablation Induces Sex-Specific Modulation of Colonic Intestinal Progenitor Cells and Response to Intestinal Injury [JW468]
In this study, we investigated regional and sex differences in the cholinergic modulation of intestinal epithelial cells in homeostasis and regeneration. Genetic intestinal epithelial ablation of the M3R employing Vil-Cre x M3R fl/fl mice interestingly resulted in the prominent reduction in Lgr5-exp...
ORGANISM(S): Mus musculus 
2025-02-28 | GSE286189 | GEO
TranscriptomicsEpithelial Muscarinic Receptor 3 Ablation Induces Sex-Specific Modulation of Colonic Intestinal Progenitor Cells and Response to Intestinal Injury [586CW]
In this study, we investigated regional and sex differences in the cholinergic modulation of intestinal epithelial cells in homeostasis and regeneration. Genetic intestinal epithelial ablation of the M3R employing Vil-Cre x M3R fl/fl mice interestingly resulted in the prominent reduction in Lgr5-exp...
ORGANISM(S): Homo sapiens 
2025-02-28 | GSE286190 | GEO
TranscriptomicsGene expression from tuft cells under scopolamine treatment
In our study, we investigated the effect of muscarinic receptor blockade on murine intestinal stem cell activity and differentiation. Following pharmacologic (scopolamine) and genetic muscarinic receptor interruption (M3R-KO, M1R-KO; Vil-Cre x M3R fl/fl, Vil-Cre x M1R fl/fl mice, respectively), we o...
ORGANISM(S): Mus musculus 
2019-11-01 | GSE138365 | GEO
UnknownDifferential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis.
Not available
S-EPMC5400569 | biostudies-literature
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