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The C. elegans gene swip-10 encodes an orphan metallo beta-lactamase that genetic studies indicate is vital for limiting neuronal excitability and viability. Sequence analysis indicates that the mammalian gene Mblac1 is the likely ortholog of swip-10, with greatest sequence identity localized...
2019-03-12 | MTBLS650 | MetaboLights
Congenital aortic valve stenosis (CAVS) affects up to 10% of the world population without medical therapies to treat the disease. New molecular targets are continually being sought that can halt CAVS progression. Collagen deregulation is a hallmark of CAVS yet remains mostly undefined. Here, histol...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021990 | Pride
A role for microRNAs has been recognized in nearly every biological system examined thus far. A complete delineation of their role must be preceded by the identification of all microRNAs present in any system. We elucidated the complete small RNA transcriptome of normal and malignant B cells through...
ORGANISM(S): Homo sapiens 

We sequenced exomes of 94 DLBCL tumors and cell lines. 34 of the tumors had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in DLBCL.

The files are associated with a manuscript submitted for publication by Callie P. Wigington et al. The main goal of this paper was to identify how calcineurin (CN) binds substrates via PxIxIT and LxVP motifs, elucidated through short linear motifs (SLiM) discovery.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-04-16 | MSV000083697 | MassIVE
The files are associated with a manuscript submitted for publication by Callie P. Wigington et al. The main goal of this paper was to identify how calcineurin (CN) binds substrates via PxIxIT and LxVP motifs, elucidated through short linear motifs (SLiM) discovery.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-04-16 | MSV000083695 | MassIVE
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