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ModelsGiantsosAdams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song...
2024-09-02 | BIOMD0000000830 | BioModels
ModelsGiantsos-Adams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song S, Sakai J, Sankaran J, Shin JH, Garcia-Carde...
2016-09-28 | MODEL1609100001 | BioModels
TranscriptomicsTranscription profiling of human soluble guanylate cyclase-deficient U937 cells exposed to the nitric oxide (NO) donor S-nitrosoglutathione to provide insight into the cGMP-independent effects of NO
NO effects on gene expression, independent of cGMP, were examined globally. Differentiated human U937 cells that lack soluble guanylate cyclase were exposed to Snitrosoglutathione, a NO donor, or glutathione without or with dibutyryl-cAMP (Bt2cAMP). NO regulated 110 transcripts that annotated dispro...
ORGANISM(S): Homo sapiens 
2007-09-11 | E-GEOD-2649 | biostudies-arrayexpress
UnknownPhase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors.
Not available
S-EPMC4606059 | biostudies-literature
ProteomicsTissue and organ matrix arrays for high throughput screening and systems analysis of cell function
Cell and protein arrays have demonstrated remarkable utility in the high-throughput evaluation of biological responses; however, they lack the complexity of native tissue and organs and cannot replicate the environment of mature normal or diseased tissues. Here, we describe the development of tissue...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2015-09-28 | PXD002571 | Pride
Tissue array Matrix Organ array Ecm 
ProteomicsLabel-free quantitative (LFQ) proteomic analysis of redox mediated posttranslational modifications (PTM) in the cartilage from young and old osteoarthritis (OA) mice with or without the senolytic treatment
Senolytic drugs are designed to selectively clear senescent cells (SnCs) that accumulate with injury or aging. In a mouse model of osteoarthritis (OA), senolysis yields a pro-regenerative response. However, recent research studies showed that the therapeutic benefit is reduced in aged mice. Increase...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-26 | PXD031782 | Pride
Mouse model of osteoarthritis (oa)  senolytic treatment  label-free quantitative (lfq) proteomic  analysis of redox ptms in the cartilage proteins 
TranscriptomicsSenescence-associated lncRNAs: senescence-associated long noncoding RNAs.
Noncoding RNAs include small transcripts, such as microRNAs and piwi-interacting RNAs, and a wide range of long noncoding RNAs (lncRNAs). Although many lncRNAs have been identified, only a small number of lncRNAs have been characterized functionally. Here, we sought to identify lncRNAs differentiall...
ORGANISM(S): Homo sapiens 
2016-02-08 | E-GEOD-77675 | biostudies-arrayexpress
TranscriptomicsRNA-Seq on SOLiD platform of DrosDel deficiency and w1118 flies
RNA-Seq reads of DrosDel deficiency (Df/+) and parental strain diploid flies along with spike-in controls was performed on the SOLiD platform. Samples are named in this dataset according to the following sample naming scheme: tissue_genotype shorthand_sex_biological replicate #_platform_technical re...
ORGANISM(S): Drosophila melanogaster 
2012-04-03 | E-GEOD-31401 | biostudies-arrayexpress
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
GenomicsBC
WTCCC1 project Breast cancer (BC) samples
EGAD00000000013 | EGA
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