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ProteomicsIntegrative metabolomics, proteomics and transcriptomics analysis reveals liver toxicity of mesoporous silica nanoparticles
As pharmaceutical excipients, mesoporous silica nanoparticles (MSNs) have attracted considerable concern based on potential risks to the public. The impact of MSNs on biochemical metabolism is poorly understood, and few studies have compared the effects of MSNs administered via different routes. To ...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-06 | PXD030757 | Pride
Proteomics Mesoporous silica nanoparticle Metabolomics Hepatotoxicity Inflammation Transcriptomic Oxidative stress Oxidative phosphorylation. 
UnknownFunctional analysis of a de novo mutation c.1692 del A of the PHEX gene in a Chinese family with X-linked hypophosphataemic rickets.
Not available
S-EPMC6719531 | biostudies-literature
UnknownA genome-wide single nucleotide polymorphism scan reveals genetic markers associated with fertility rate in Chinese Jing Hong chicken.
Not available
S-EPMC7597651 | biostudies-literature
UnknownIdentification of biomarkers and mechanism exploration of ferroptosis related genes regulated by m6A in type 2 diabetes mellitus.
Not available
S-EPMC11834627 | biostudies-literature
UnknownThe FcεRI signaling pathway is involved in the pathogenesis of lacrimal gland benign lymphoepithelial lesions as shown by transcriptomic analysis.
Not available
S-EPMC8576038 | biostudies-literature
UnknownCarotenoid Cleavage Dioxygenase Genes of Chimonanthus praecox, CpCCD7 and CpCCD8, Regulate Shoot Branching in Arabidopsis.
Not available
S-EPMC8395739 | biostudies-literature
UnknownHumanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors.
Not available
S-EPMC9910454 | biostudies-literature
MetabolomicsModulation of liver metabolism and gut microbiota by Alhagi-honey alleviated heat stress-induced liver damage

Alhagi-honey (AH) is a well-established traditional ethnic medicine with advantageous effects against diarrhea and headaches. We aim to explore the preventive effect of AH on liver damage induced by heat stress (HS) and its underlying mechanism. HS models were established by thermostat, and mice ...

2024-09-23 | MTBLS10021 | MetaboLights
UnknownEfficient Stereospecific Hβ2/3 NMR Assignment Strategy for Mid-Size Proteins.
Not available
S-EPMC6513325 | biostudies-literature
TranscriptomicsFunctional Evidence Implicating Chromosome 7q22 Haploinsufficiency in Myelodysplastic Syndrome Pathogenesis
Purpose: 5A3+/del mice, which have a heterozygous germ line deletion of a 2-Mb interval of chromosome band 5A3 syntenic to a commonly deleted segment of human 7q22, exhibit hematopoietic stem cell (HSC) abnormalities that may contribute to myelodysplastic syndrome (MDS) pathogenesis. These defects a...
ORGANISM(S): Mus musculus 
2015-09-09 | E-GEOD-72811 | biostudies-arrayexpress
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