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MetabolomicsA machine learning model for the prediction and verification of the protective intestinal microbiota-derived L-valine in sepsis

The intestinal microflora and metabolites produced by these microbes serve as important regulators of the development of sepsis. Accordingly, this study was designed to systematically explore the relationships between the regulation of septicemia and both the intestinal flora and fecal metabolite...

2023-07-28 | MTBLS7866 | MetaboLights
TranscriptomicsTranscriptional comparison of the filamentous fungus Neurospora crassa growing on three major monosaccharides D-glucose, D-xylose and L-arabinose
D-glucose, D-xylose and L-arabinose are three major monosaccharides in the plant cell wall. Complete utilization of all three sugars is still a bottleneck for second-generation cellulolytic bioethanol production, especially for L-arabinose. However, little is known about the gene expression profiles...
ORGANISM(S): Neurospora crassa 
2014-03-17 | E-GEOD-51091 | biostudies-arrayexpress
TranscriptomicsImpact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-l-galactose phosphorylase
The l-galactose (Smirnoff-Wheeler) pathway represents the major route to l-ascorbic acid (vitamin C) biosynthesis in plants. Arabidopsis thaliana VTC2 and its paralogue VTC5 function as GDP-l-galactose phosphorylases converting GDP-l-galactose to l-galactose-1-P, thus catalyzing the first committed ...
ORGANISM(S): Chlamydomonas reinhardtii 
2012-05-02 | E-GEOD-34826 | biostudies-arrayexpress
TranscriptomicsLactobacillus johnsonii NCC comparative genomics with L. iatae
Whole genome DNA microarray designed for the probiotic L. johnsonii strain NCC533 was used for comparative genomic hybridization (CGH) of L. johnsonii ATCC 33200T, L. johnsonii BL261, L. gasseri ATCC 33323T and L. iatae BL263 (CECT 7394T). In these experiments, the fluorescence ratio distributions o...
ORGANISM(S): Lactobacillus johnsonii 
2010-11-24 | E-GEOD-21627 | biostudies-arrayexpress
ProteomicsSystematic analysis of lysine 2-hydroxyisobutyrylation in Rheum palmatum L． leaves
Lysine 2-hydroxyisobutyrylation (Khib) is a recently discovered posttranslational modification (PTM). Its structure characterization and function illustration have been reported in some species. However, the study of Khib in plant species is still relatively limited.Rheum palmatum L. is a global imp...
ORGANISM(S): Rheum palmatum 
2021-05-29 | PXD026307 | Pride
Lc-ms/ms Lysine 2-hydroxyisobutyrylation Rheum palmatum l 
ProteomicsFast Profiling of Protease Specificity reveals similar substrate specificities for cathepsins K, L and S
N-terminal COFRADIC analysis of cathespine K, L and S to obtain the substrate specificity profile of these cysteine cathepsins.
ORGANISM(S): Homo sapiens (Human) 
2015-02-10 | PXD001536 | Pride
Cathespins N-terminal cofradic 
ProteomicsProteomics reveals virulence-related proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii yeast cells grown in the presence of L-dihydroxyphenylalanine
Species of the genus Paracoccidioides cause a systemic infection in human patients. Yeast cells of Paracoccidioides spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen survival into the host. To better understand the metabolic changes ...
ORGANISM(S): Fungi Paracoccidioides brasiliensis (strain Pb18) Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis) 
2021-01-20 | PXD021711 | Pride
L-dihydroxyphenylalanine Proteomics Virulence Melanin Paracoccidioides 
ProteomicsThreonine concentration effect on L. lactis growth
L. lactis was grown in steady-state cultures at specific growth rate 0.2 h-1. The concentration of L-threonine in the growth environment was smoothly increased from 1.24mM to 4mM and proteome measurements were carried out to detect proteins involved in threonine metabolism.
ORGANISM(S): Lactococcus lactis 
2015-03-19 | PXD001602 | Pride
Lactococcus lactis Silac Threonine metabolism 
ProteomicsCharacterization of a L-Gulono-1,4-Lactone Oxidase Like Protein in the Floral Nectar of Mucuna sempervirens, Fabaceae.
Floral nectar plays important roles in the interaction between animal-pollinated plants and pollinators. Growing empirical evidence shows that most of the proteins secreted in nectar (nectarins) are enzymes that can tailor nectar chemistry for their animal mutualists or reduce the growth of microorg...
ORGANISM(S): Mucuna sempervirens 
2018-08-16 | PXD010067 | Pride
L-ascorbate biosynthesis  l-gulonolactone oxidase like protein  mucuna sempervirens hemsl  nectarin 
TranscriptomicsTranscriptomic analysis of grape (Vitis vinifera L.) leaves exposed to ultraviolet C radiation
Solar ultraviolet C（UV-C）radiation reaching the Earth’s surface is little due to the filtering effects of the stratospheric ozone layer. At present, artificial UV-C irradiation is utilized for different biological processes. Grape is a major fruit crop around the world. Research has shown that UV-C ...
ORGANISM(S): Vitis vinifera 
2014-11-15 | E-GEOD-62315 | biostudies-arrayexpress
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