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Insulin resistance and Type 2 diabetes are marked by an aberrant response in the insulin signaling network. The phosphoinositide-dependent serine/threonine kinase, Akt2, plays a key role in insulin signaling and glucose uptake, most notably within skeletal muscle. Protein-protein interaction regul...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-30 | PXD002557 | Pride
Obesity-related insulin resistance (OIR) is one of the main contributors to type 2 diabetes and other metabolic diseases. Protein kinases are implicated in key signaling steps including insulin signaling and glucose metabolism. Molecular mechanisms underlying OIR involving global active kinases rema...
ORGANISM(S): Homo sapiens (Human) 
2020-01-23 | PXD011909 | Pride
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