Sort   by:  
 Page size 
ProteomicsAkt2 partners L6 myoblasts - Novel Endogenous, Insulin-Stimulated Akt2 Protein Interaction Partners in L6 Myoblasts
Insulin resistance and Type 2 diabetes are marked by an aberrant response in the insulin signaling network. The phosphoinositide-dependent serine/threonine kinase, Akt2, plays a key role in insulin signaling and glucose uptake, most notably within skeletal muscle. Protein-protein interaction regul...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-30 | PXD002557 | Pride
Akt2 Hplc-esi-ms/ms Rock2 
TranscriptomicsMyocardial expression data from wild-type and akt2-/- mice
Wild-type (WT) C57Bl/6 and akt2-/- male mice. Keywords: RNA Expression Array Left ventricles (LV) from 12-16 week-old male wild type mice and age-matched akt2-/- mice
ORGANISM(S): Mus musculus 
2010-11-19 | E-GEOD-19079 | biostudies-arrayexpress
TranscriptomicsExpansion of hepatic tumor progenito cell population in PTEN deficient mice requires liver injury and is reversed by deletion of Akt2
We found that hepatic injury induced by PTEN loss establishes a selection pressure for tumorinitiating cells (TICs) to proliferate and form mixed lineage tumors. The Pten null mice demonstrate escalating levels of hepatic injury prior to proliferation of hepatic progenitors. Attenuation of hepatic i...
ORGANISM(S): Mus musculus 
2016-03-31 | E-GEOD-70501 | biostudies-arrayexpress
ProteomicsAKT2 interacting proteins_ MBP- and MAP-TAPs
Tagged AKT2 was expressed in HEK293T cells. For quantification SILAC labeling was performed. MBP-TAP: Cell lysates were mixed at a 1:1 ratio with unlabeled wild type cells before Tandem Affinity Purification. MAP-TAP: Same amount of labeled and unlabeled cell lysates were purified via Tandem Affinit...
ORGANISM(S): Homo sapiens (Human) 
2013-08-13 | PXD000197 | Pride
Human Ltq-orbitrap Akt2 Hek293t Tap 
TranscriptomicsGene expression analysis of Akt2 deficient murine naive CD4 T cells cultured in Th17-polarizing conditions for 36 hours
Akt1 and Akt2, isoforms of the serine threonine kinase Akt, are essential for T cell development. However, their role in peripheral T cell differentiation remains undefined. Using mice with germline deletions of either Akt1 or Akt2, we found that both isoforms are important for Th17 differentiatio...
ORGANISM(S): Mus musculus 
2016-07-03 | E-MTAB-4062 | biostudies-arrayexpress
TranscriptomicsEffect of cardiomyocyte specific KO of AKT1, AKT2, and AKT1 + AKT2 on gene expression profile of the heart
In the mammalian heart AKT1 and AKT2 are the isoforms of the protein kinase AKT (protein kinase B) which are predominantly expressed. AKT isoforms exert common and specific functions in the field of metabolism, cellular growth, apoptosis and cell migration. To identify specific and common functions ...
ORGANISM(S): Mus musculus 
2017-11-30 | GSE86231 | GEO
TranscriptomicsRNA-seq data from livers of 6 month old Akt1F/F;Akt2-/- versus Akt1F/F;Akt2-/-;Alb-Cre mice
Finding diffrential gene expression gene expression in the livers of male mice after the deletion of Akt1 in th eliver of Akt2-/- mice.
ORGANISM(S): Mus musculus 
2016-04-30 | GSE77862 | GEO
TranscriptomicsMyocardial expression data from wild-type and akt2-/- mice
Wild-type (WT) C57Bl/6 and akt2-/- male mice. Keywords: RNA Expression Array
ORGANISM(S): Mus musculus 
2010-11-19 | GSE19079 | GEO
GenomicsThe AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD
PRJNA1124124 | ENA
UnknownRecurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma.
Not available
S-EPMC4371965 | biostudies-literature
Sort   by:  
 Page size