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ProteomicsDiscovering biomarkers for non-alcoholic steatohepatitis pa-tients with and without hepatocellular carcinoma using fecal metaproteomics
High-calorie diets lead hepatic steatosis and to the development of non-alcoholic fatty liver disease (NAFLD), which can evolve over many years into the inflammatory form non-alcoholic steatohepatits (NASH) posing a risk for the development of hepatocellular carcinoma (HCC). Due to the diet and the ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD034175 | Pride
Non-alcoholic steatohepatitis Metaproteomics Hepatocellular carcinoma Fecal microbiota Ma-chine learning 
ProteomicsApplication of SWATH Mass Spectrometry and Machine Learning in Diagnosis of Inflammatory Bowel Disease Based on Stool Proteome
Our hypothesis was that conducting proteomic analysis on clinical laboratory samples which are intended for the fecal calprotectin test would enable the develop-ment of a highly sensitive and specific non-invasive stool test based on mass spec-trometry. To investigate this hypothesis, we combined an...
ORGANISM(S): Homo sapiens (Human) 
2024-02-01 | PXD047585 | Pride
Human Inflammatory bowel disease. Stool 
ProteomicsA First-Trimester Serum Proteomic Signature for Early Predic-tion of Preeclampsia: Integrated Untargeted and Targeted Mass Spectrometry with Machine Learning
First-trimester prediction of preeclampsia (PE) remains a major clinical challenge, par-ticularly outside specialized fetal medicine centers. This study aimed to identify and validate serum protein biomarkers for early PE prediction using an integrated proteo-mic approach. A prospective cohort of 64...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD080843 | Pride
Preeclampsia  first-trimester screening  serum proteomics  prognosis  dia-ms  mrm-ms  machine learning  biomarkers  complement system  mass spectrometry. 
UnknownInterpretable Machine Learning Approach for Predicting 30-Day Mortality of Critical Ill Patients with Pulmonary Embolism and Heart Failure: A Retrospective Study.
Not available
S-EPMC11618897 | biostudies-literature
UnknownAutomated in-depth cerebral arterial labelling using cerebrovascular vasculature reframing and deep neural networks.
Not available
S-EPMC9957982 | biostudies-literature
UnknownImplementing Symptom-Based Predictive Models for Early Diagnosis of Pediatric Respiratory Viral Infections.
Not available
S-EPMC12031125 | biostudies-literature
UnknownAdditional SNPs improve risk stratification of a polygenic hazard score for prostate cancer.
Not available
S-EPMC8157993 | biostudies-literature
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