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MetabolomicsMaternal blood lipidomics associated with severe preeclampsia
Not available
ORGANISM(S): Homo sapiens 
ST001360 | MetabolomicsWorkbench
MetabolomicsIntegrative Exposomic, Transcriptomic, Epigenomic Analyses of Human Placental Samples Links Understudied Chemicals to Preeclampsia
Not available
ORGANISM(S): Homo sapiens 
ST002151 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human adipose tissue, decidua and placenta from patients with preeclampsia vs. unaffected indviduals reveals dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia
Preeclampsia complicates more than 3% of all pregnancies in the United States and Europe. High-risk populations include women with diabetes, dyslipidemia, thrombotic disorders, hyperhomocysteinemia, hypertension, renal diseases, previous preeclampsia, twin pregnancies, and low socioeconomic status. ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6573 | biostudies-arrayexpress
TranscriptomicsSevere preeclampsia: new blood circulating biomarkers
Background: Preeclampsia (PE) is a placental disease characterized by hypertension and proteinuria in pregnant women, which is associated with a high maternal and infantile morbidity. However, circulating biomarkers able to predict the prognosis of PE are lacking. Methods: Thirty-eight women were in...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-48424 | biostudies-arrayexpress
TranscriptomicsPlacental gene expression in severe preeclampsia.
The series is composed of thirty hybridizations for analysis of differentially expressed genes in normal placenta tissues from patients with normal labor and placenta tissues from patients with severe preeclampsia. Patients tissues samples were obtained from (Vasilis. Total RNA extraction was perfor...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10588 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human chorionic villus samples from preeclampsia patients
4 chorionic villus sampling specimens in pregnancies destined for preeclampsia and 8 matched controls were analyzed; 36 genes were differentially expressed using J5 score and prediction modeling in caGEDA computer program Experiment Overall Design: case-control comparisons
ORGANISM(S): Homo sapiens 
2008-11-29 | E-GEOD-12767 | biostudies-arrayexpress
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 2
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-02 | MSV000085361 | MassIVE
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 1
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-01 | MSV000085357 | MassIVE
ProteomicsMultiomics reveals placental defect underlying preeclampsia
Preeclampsia is a serious pregnancy-induced disorder unique to humans affecting 4.6% of pregnancies worldwide. Advances in the detection, prevention and treatment of preeclampsia have been poor due to our inadequate understanding of its pathogenesis. Here, we perform a multiomics study on early preg...
ORGANISM(S): Homo sapiens (Human) 
2026-06-10 | PXD059993 | Pride
Multiomics Preeclampsia Placental defects Placenta Cvs 
TranscriptomicsSevere Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Siglec-6 and Pappalysin-2
Preeclampsia (PE), which affects 4-8% of human pregnancies, causes significant maternal and neonatal morbidity and mortality. Within the basal plate, placental cytotrophoblasts (CTBs) of fetal origin invade the uterus and extensively remodel the maternal vasculature. In PE, CTB invasion is often sha...
ORGANISM(S): Homo sapiens 
2009-02-06 | E-GEOD-14722 | biostudies-arrayexpress
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