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TranscriptomicsModification of T cell responses by stem cell mobilization requires direct signalling of the T cell by G-CSF and IL-10
The majority of allogeneic stem cell transplants are currently undertaken using G-CSF mobilized peripheral blood stem cells. G-CSF has diverse biological effects on a broad range of cells and IL-10 is a key regulator of many of these effects. Using mixed radiation chimeras in which the haematopoieti...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-54616 | biostudies-arrayexpress
UnknownAlpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK.
Not available
S-EPMC10729141 | biostudies-literature
UnknownImaging Modality and Frequency in Surveillance of Stage I Seminoma Testicular Cancer: Results From a Randomized, Phase III, Noninferiority Trial (TRISST).
Not available
S-EPMC7614664 | biostudies-literature
UnknownAltered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: a preliminary study.
Not available
S-EPMC3245800 | biostudies-literature
TranscriptomicsTc17 cells are a pro-inflammatory, plastic lineage of pathogenic CD8+ T-cells that induce GVHD without anti-leukemic effects
IL-17-producing cells are important mediators of graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (SCT). Here we demonstrate that a distinct CD8+ Tc17 population develops rapidly after SCT but fails to maintain lineage fidelity such that they are unrecognizable in the abse...
ORGANISM(S): Mus musculus 
2015-09-13 | E-GEOD-70931 | biostudies-arrayexpress
UnknownPlasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Not available
S-EPMC11869088 | biostudies-literature
UnknownCabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.
Not available
S-EPMC5024539 | biostudies-literature
UnknownOutpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK.
Not available
S-EPMC12862379 | biostudies-literature
UnknownOpen science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Not available
S-EPMC7615835 | biostudies-literature
UnknownSARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Not available
S-EPMC8709832 | biostudies-literature
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