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ModelsMacNamara2012 - Signal transduction
MacNamara2012 - Signal transduction A toy model of signal tranduction to illustrate how different logic formalizms (Boolean, fuzzy logic and differential equations) treat state and time, is described here. This model was generated from the PKN-ToyPB.sif file available in...
2005-01-01 | MODEL1305240000 | BioModels
TranscriptomicsRNA-seq analysis of 2 cell line models of lung disease (A549 and BEAS-2B) and primary bronchial epithelial cells in Project 3 of Open Targets 020 - Epigenomes of Cell Lines
This experiment captures the baseline expression of two cell lines (A549, BEAS-2B) selected for Project 3, Open Targets 020 (http://opentargets.org). These cell lines are both possible models for lung disease. In addition, the baseline expression of bronchial epithelial primary cells (NHBE cells) fr...
ORGANISM(S): Homo sapiens 
2017-07-04 | E-MTAB-4729 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of cell-line models for monocyte to macrophage transformation: Project 2 of Open Targets - Epigenomes of Cell Lines
The goal of this experiment is to characterize the expression of two cell-line models of monocyte to macrophage transformation, U937 and THP-1. Either PMA (phorbol myristate acetate) and LPS (lipopolysaccharide) or VD3 (vitamin D3) and LPS were used as stimuli to induce differentiation.
The foll...
ORGANISM(S): Homo sapiens 
2016-10-22 | E-MTAB-5191 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of six cell line models for haematopoiesis: Project 1 of Open Targets - Epigenomes of Cell Lines
This experiment captures the baseline expression of 6 cell lines (K562, KU812, MEG01, HEL9217, F36-P, UT7) selected for Project 1, Open Targets 020. These cell lines are all possible cell models for haematopoiesis.
This RNA-seq experiment is being carried out as part of the Open Targets project t...
ORGANISM(S): Homo sapiens 
2016-01-27 | E-MTAB-4101 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of two common T cell models, HUT78 and JURKAT E6.1: Project 5 of Open Targets - Epigenomes of Cell Lines
The aim of this experiment was to characterize the gene expression of two common immortalized T cell lines (HUT78 and JURKAT E6.1) with and without activating stimuli. Two independent cultures were carried out for each of the cell lines. Cells were cultured according to supplier recommendations and ...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-6869 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of several immortalized B cell lines (Namalwa, Daudi, Ramos, Raji, Toledo, ARH-77): Project 6 of Open Targets - Epigenomes of Cell Lines
The aim of this experiment was to characterize the gene expression of several immortalized B cell lines (Namalwa, Daudi, Ramos, Raji, Toledo, ARH-77). Two independent cultures were carried out for each of the cell lines. Cell lines were grown using supplier recommended culture methods and harvested ...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-6867 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of several in vitro models of hepatocyte function: Project 4 of Open Targets - Epigenomes of Cell Lines
The aim of this experiment was to characterize the gene expression of several in vitro cellular models of hepatocyte function: primary hepatocytes and common immortalized liver cell lines (HepG2, Hep3B and Huh7), cultured in parallel in both 2D and 3D configurations. Two independent cultures were c...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-6870 | biostudies-arrayexpress
ModelsTerfve2012 - Signalling in liver cancer - logical model
No description
2015-06-26 | MODEL1506260000 | BioModels
UnknownData- and knowledge-derived functional landscape of human solute carriers
Not available
S-SCDT-10_1038-S44320-025-00108-2 | biostudies-other
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