Sort   by:  
 Page size 
To identify the transcriptome divergence and sex roles underlying it in recently diverged Drosophia pseudoobscura group, we compare the global gene expression of 7-day-old whole body adults of pure species. 7-day-old virgin flies were assayed by species and sex. At least three isofemale inbred line...
ORGANISM(S): Drosophila persimilis 
Understanding the genetic basis of adaptation to novel environments remains one of the major challenges confronting evolutionary biologists. While newly developed genomic approaches hold considerable promise for addressing this overall question, the relevant tools have not often been available in t...
ORGANISM(S): Drosophila mojavensis 
To profile the human substrate degradome of the SARS-CoV-2 main viral protease and to investigate whether 3CLpro cleavage of cellular substrates dampens host antiviral responses induced by type I interferons, we treated BEAS-2B cells with interferon-alpha (N = 3), interferon-beta (N = 3), or vehicle...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD026815 | Pride
To profile the human substrate degradome of the SARS-CoV-2 main viral protease by exposingnative proteome extracts from human embryonic kidney (HEK-293) cells (N = 3) to 3CLpro cleavage. Then, N Terminal Amine Labeling of Substates (TAILS) was used to identify the substrates. Here, heavy [+34] isoto...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD026797 | Pride
The present study aimed to develop and optimize cell derived membrane-coated nanostructures by applying a design of experiments (DoE) to improve the therapeutic index by homotypic targeting in cancer cells. The protein composition of the extracted cell membrane from tumoral cells were assessed by ma...
ORGANISM(S): Homo sapiens (Human) 
2023-01-31 | PXD039270 | Pride
Sort   by:  
 Page size