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TranscriptomicsStructural polymorphism in the promoter of pfmrp2 confers tolerance to mefloquine and chloroquine in Plasmodium falciparum [CGH]
Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
2013-02-07 | E-GEOD-44128 | biostudies-arrayexpress
TranscriptomicsThe Variantome of the malaria parasite Plasmodium falciparum.
We compared transcript levels at several points along the asexual blood cycle between 21 P. falciparum lines. These 21 parasite lines are organized in 4 sets of parasite lines, with all parasite lines within a set sharing a clonal origin. We compared transcript levels within each set. We also perfor...
ORGANISM(S): Plasmodium falciparum 
2012-02-07 | E-MTAB-673 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of Imatinib resistance in CD34+ cell populations from chronic myeloid leukaemia patients using Agilent-014698 Whole Human Genome 105K microarrays.
To ascertain genomic alterations associated with Imatinib resistance in chronic myeloid leukaemia, we performed high resolution genomic analysis of CD34+ cells from 25 Imatinib (IM) resistant and 11 responders CML patients. Using patients' T-cells as reference, we found significant association betwe...
ORGANISM(S): Homo sapiens 
2010-11-15 | E-GEOD-21986 | biostudies-arrayexpress
TranscriptomicsAgilent 244A aCGH array for breast, lung, melanoma, ovary, and prostate
373 tumors were profiled for copy-number alterations with the high-resolution Agilent 244A aCGH Array. Tumor samples were assayed on Agilent Human Genome CGH 244A Microarrays with the intent of surveying the landscape of genomic alterations in 5 tumor types. Human male genomic DNA (Promega P/N G1471...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-20393 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of new cyanphage isolates against an array with probes designed against the core genome of the four cyanophage isolates S-PM2, Syn9, P-SSM2 and P-SSM4
Comparative genomic hybridisations of new cyanphage isolates against an array with probes designed against the core genome of the four cyanophage isolates S-PM2, Syn9, P-SSM2 and P-SSM4
ORGANISM(S): Synechococcus phage S-IO17 
2009-02-01 | E-MAXD-45 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of human de novo actue myeloid leukemia (p-AML) samples and normal samples
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-TABM-1014 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of the transcriptome in the primate corpus luteum during chorionic gonadotropin administration simulating early pregnancy.
To explore chorionic gonadotropin (CG)-regulated gene expression in the primate corpus luteum (CL), adult female rhesus macaques were treated with a model of simulated early pregnancy (SEP). Total RNA was isolated from individual CL and hybridized to AffymetrixM-bM-^DM-" GeneChip Rhesus Macaque Geno...
ORGANISM(S): Macaca mulatta 
2011-11-21 | E-GEOD-25335 | biostudies-arrayexpress
TranscriptomicsGenomic aberrations in distant fields from oral potentially malignant lesions by high resolution DNA flow cytometry and array-CGH
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28906 | biostudies-arrayexpress
TranscriptomicsA general framework for optimization of probes for gene expression microarray and its application to the fungus Podospora anserina
A genome wide microarray, covering the 10546 presently known and predicted CDS, has been constructed with the Agilent in-situ synthesized 60-mers technology. 1) A library of 10 oligonucleotides per CDS has been design by the manufacturer. 2) A computational step has been performed to determine 3' po...
ORGANISM(S): Podospora anserina 
2010-06-30 | E-GEOD-20734 | biostudies-arrayexpress
UnknownExamining the impact of trimester of diagnosis on COVID-19 disease progression in pregnancy.
Not available
S-EPMC9391234 | biostudies-literature
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