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TranscriptomicsTranscription profiling of mouse splenic CD4+ cells after surgical induction of sepsis vs. controls reveals a distinct transcriptional response 6 hours after sepsis induction
Lymphocytes are adversely affected during sepsis. Some CD4+ splenocytes undergo apoptosis while others become Th2 polarized. The molecular determinants of these phenotypic changes are not known. Here we compare the transcriptional response of septic CD4 splenocytes to CD4 splenocytes from sham-manip...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4479 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse models of sepsis cecal ligation and puncture and tracheal instillation of P. aeruginosa reveals bcl-2 overexpression modulates transcription responses in vivo
Background: We hypothesized that spleen microarray gene expression profiles analyzed with contemporary pathway analysis software would provide molecular pathways of interest and target genes that might help explain the affect of bcl-2 on improving survival during sepsis. Methods: Two mouse models of...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5811 | biostudies-arrayexpress
UnknownCSHP Professional Practice Conference 2019: Poster Abstracts
Not available
S-EPMC6391241 | biostudies-literature
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