Macropinocytosis

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Unknown (709)
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protozoa (1)
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Transcription profiling by array (3)

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Duke University (1)
Dapartment of Biochemistry, Molecular and Structural Biology Jozef Stefen Institute Ljubljana, Slovenia (1)
Biomedical Research Foundation Academy of Athens- BRFAA, Centre of Basic Research, Athens, Greece (1)
International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland (1)
Tranlational Oncology Group, Center for Tumor Biology and Immunology, Philipps University, Marburg, Germany (1)
Princeton University (1)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (1)
Laboratory of Cell Biology, National Cancer Institute, NIH United States (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)

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Identification of ATP9A interactors in 293T cell line

Macropinocytosis is an effective strategy against nutrient starvation, which fuels cancer cells grow in nutrient-limited conditions. However, whether and how macropinocytosis contributes to the rapid proliferation of hepatocellular carcinoma cells that frequently exhibit inadequate nutrient supply r...

ORGANISM(S): Homo Sapiens

2022-12-13 | PXD038797 |

Cell polarity proteins promote macropinocytosis in response to metabolic stress

PRJNA1154268 | ENA

Macropinocytosis promotes foamy monocyte formation in hypercholesterolemic mice

PRJNA1165711 | ENA

Progestin receptor promotes cell macropinocytosis through CDC42 in pancreatic cancer

PRJNA949219 | ENA

¬Macropinocytosis mediates metabolic resistance to loss of glutamine transport in triple-negative breast cancer

Although a nonessential amino acid in normal cells, the demand for glutamine is dramatically increased throughout malignant transformation, supporting a range of metabolic processes including mitochondrial ATP production, protein synthesis, purine and pyrimidine biosynthesis. We previously showed th...

ORGANISM(S): Homo sapiens (Human)

2024-09-16 | PXD053894 | Pride

Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer [nanoString nCounter]

PRJNA1283083 | ENA

Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis

PRJNA1271514 | ENA

Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis

PRJNA1278998 | ENA

Cell polarity proteins promote macropinocytosis in response to metabolic stress

Macropinocytosis has emerged as a nutrient-scavenging pathway that cancer cells exploit to survive the nutrient-deprived conditions of the tumor microenvironment. Cancer cells are especially reliant on glutamine for their survival, and in pancreatic ductal adenocarcinoma (PDAC) cells, glutamine defi...

ORGANISM(S): Homo sapiens

2024-10-22 | GSE276007 | GEO

Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells

PRJNA727010 | ENA

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